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Index > Protein center > Bcl3(Gene name) > Mouse
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  • Bcl3 (Gene name),
  • B-cell lymphoma 3 protein homolog (Protein name ),  BCL3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Bcl3;
    Protein name:
    B-cell lymphoma 3 protein homolog(BCL-3);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2, COPS5 and PIR (By similarity). Interacts with CYLD.
    Function:
    Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity). In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation.
    Subcellular Location:
    Nucleus Cytoplasm Cytoplasm perinuclear region Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MPRCPAGAMD | EGPVDLRTRP | KGTPGAALPL | RKRPLRPASP | EPATTRSPAG | 
    100:
    PLDALRSGCD | VPVVPGPPHC | VARPEALYYQ | GPLMPIYSTP | TMAPHFPLLN | 
    150:
    LPTHPYSMIC | PMEHPLSADI | AMATRVDEDG | DTPLHIAVVQ | NNIAAVYRIL | 
    200:
    SLFKLGSREV | DVHNNLRQTP | LHLAVITTLP | DMVRLLVTAG | ASPMALDRHG | 
    250:
    QTAIHLACEH | RSPSCLQALL | DSATSGSVDL | EVRNYEGLTA | LHVAVNTGCQ | 
    300:
    EAVLLLLERG | ADIDAVDIKS | GRSPLIHAVE | NNSLNMVQLL | LLHGANVNAQ | 
    350:
    MYSGSSALHS | ASGRGLLPLV | RTLVRSGADS | GLKNCHNDTP | LMVARSRRVI | 
    400:
    DILRGKASRA | ASGSQPEPSP | DQSATNSPES | SSRLSSNGLQ | SSPSSSPSLS | 
    448:
    PPKDAPGFPA | TPQNFFLPTT | STPAFLPFPG | VLRGPGRPVP | PSPAPGSS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse BCL-3
    Cat.:
    E1734h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BCL-3
    Cat.:
    E1734m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BCL-3
    Cat.:
    U1734h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse BCL-3
    Cat.:
    U1734m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse BCL-3
    Cat.:
    P1734Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse BCL-3
    Cat.:
    P1734Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse BCL-3
    Monoclonal Antibody for Mouse BCL-3
    Protein for Mouse BCL-3
    Protein for Mouse BCL-3

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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "Interleukin-9 regulates NF-kappaB activity through BCL3 gene induction."
      Richard M. , Louahed J. , Demoulin J.-B. , Renauld J.-C.
      Blood93:4318-4327(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    3. 3.
      "Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling."
      Massoumi R. , Chmielarska K. , Hennecke K. , Pfeifer A. , Fassler R.
      Cell125:665-677(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CYLD;SUBCELLULAR LOCATION
    4. 4.
      "CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin."
      Wickstrom S.A. , Masoumi K.C. , Khochbin S. , Fassler R. , Massoumi R.
      EMBO J.29:131-144(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CYLD
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