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Index > Protein center > BCLAF1(Gene name) > Human
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  • BCLAF1 (Gene name),
  • Bcl-2-associated transcription factor 1 (Protein name ),  BCLF1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BCLAF1(BTF;KIAA0164);
    Protein name:
    Bcl-2-associated transcription factor 1(Btf);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.
    Function:
    Death-promoting transcriptional repressor.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    920
    Sequence:
    50:
    MGRSNSRSHS | SRSKSRSQSS | SRSRSRSHSR | KKRYSSRSRS | RTYSRSRSRD | 
    100:
    RMYSRDYRRD | YRNNRGMRRP | YGYRGRGRGY | YQGGGGRYHR | GGYRPVWNRR | 
    150:
    HSRSPRRGRS | RSRSPKRRSV | SSQRSRSRSR | RSYRSSRSPR | SSSSRSSSPY | 
    200:
    SKSPVSKRRG | SQEKQTKKAE | GEPQEESPLK | SKSQEEPKDT | FEHDPSESID | 
    250:
    EFNKSSATSG | DIWPGLSAYD | NSPRSPHSPS | PIATPPSQSS | SCSDAPMLST | 
    300:
    VHSAKNTPSQ | HSHSIQHSPE | RSGSGSVGNG | SSRYSPSQNS | PIHHIPSRRS | 
    350:
    PAKTIAPQNA | PRDESRGRSS | FYPDGGDQET | AKTGKFLKRF | TDEESRVFLL | 
    400:
    DRGNTRDKEA | SKEKGSEKGR | AEGEWEDQEA | LDYFSDKESG | KQKFNDSEGD | 
    450:
    DTEETEDYRQ | FRKSVLADQG | KSFATASHRN | TEEEGLKYKS | KVSLKGNRES | 
    500:
    DGFREEKNYK | LKETGYVVER | PSTTKDKHKE | EDKNSERITV | KKETQSPEQV | 
    550:
    KSEKLKDLFD | YSPPLHKNLD | AREKSTFREE | SPLRIKMIAS | DSHRPEVKLK | 
    600:
    MAPVPLDDSN | RPASLTKDRL | LASTLVHSVK | KEQEFRSIFD | HIKLPQASKS | 
    650:
    TSESFIQHIV | SLVHHVKEQY | FKSAAMTLNE | RFTSYQKATE | EHSTRQKSPE | 
    700:
    IHRRIDISPS | TLRKHTRLAG | EERVFKEENQ | KGDKKLRCDS | ADLRHDIDRR | 
    750:
    RKERSKERGD | SKGSRESSGS | RKQEKTPKDY | KEYKSYKDDS | KHKREQDHSR | 
    800:
    SSSSSASPSS | PSSREEKESK | KEREEEFKTH | HEMKEYSGFA | GVSRPRGTFF | 
    850:
    RIRGRGRARG | VFAGTNTGPN | NSNTTFQKRP | KEEEWDPEYT | PKSKKYFLHD | 
    900:
    DRDDGVDYWA | KRGRGRGTFQ | RGRGRFNFKK | SGSSPKWTHD | KYQGDGIVED | 
    920:
    EEETMENNEE | KKDRRKEEKE | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    String:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Btf
    ELISA Kit for Human Btf
    CLIA Kit for Human Btf
    CLIA Kit for Human Btf
    Polyclonal Antibody for Human Btf
    Polyclonal Antibody for Human Btf
    Monoclonal Antibody for Human Btf
    Monoclonal Antibody for Human Btf
    Protein for Human Btf
    Protein for Human Btf

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Btf, a novel death-promoting transcriptional repressor that interacts with Bcl-2-related proteins."
      Kasof G.M. , Goyal L. , White E.
      Mol. Cell. Biol.19:4390-4404(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3)
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."
      Nagase T. , Seki N. , Ishikawa K. , Tanaka A. , Nomura N.
      DNA Res.3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Bone marrow.
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORM 1)
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-676 (ISOFORM 4)
      tissue: Brain.
      tissue: Pancreas.
      tissue: Testis.
      tissue: Uterus.
    6. 6.
      Bienvenut W.V. , Heiserich L. , Boulahbel H. , Gottlieb E.
      Submitted (2008-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 168-182; 189-204; 256-271; 284-298; 304-312; 319-332; 394-409; 422-439; 461-475; 505-517; 525-534; 537-548; 551-581; 587-593; 623-631; 654-664; 785-796; 832-842 AND 846-852;PHOSPHORYLATION AT SER-177; SER-268; SER-290; SER-512; SER-531 AND SER-658;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
    7. 7.
      "Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy."
      Haraguchi T. , Holaska J.M. , Yamane M. , Koujin T. , Hashiguchi N. , Mori C. , Wilson K.L. , Hiraoka Y.
      Eur. J. Biochem.271:1035-1045(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EMD
    8. 8.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-389; SER-397; THR-402; SER-531 AND SER-648;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line."
      Giorgianni F. , Zhao Y. , Desiderio D.M. , Beranova-Giorgianni S.
      Electrophoresis28:2027-2034(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Prostate cancer.
    10. 10.
      "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."
      Yu L.R. , Zhu Z. , Chan K.C. , Issaq H.J. , Dimitrov D.S. , Veenstra T.D.
      J. Proteome Res.6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SNARP COMPLEX
    12. 12.
      "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
      Carrascal M. , Ovelleiro D. , Casas V. , Gay M. , Abian J.
      J. Proteome Res.7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-397;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: T-cell.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181; SER-222; SER-264; SER-268; TYR-284; SER-290; THR-341; SER-385; SER-389; SER-397; THR-402; SER-512; SER-531; SER-578 AND SER-658;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    14. 14.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177 AND SER-397;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    15. 15.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-222; SER-290; SER-385; SER-397; THR-402 AND SER-512;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    17. 17.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-152 AND LYS-437;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102; SER-104; SER-177; SER-196; SER-198; SER-222; SER-268; SER-290; SER-297; SER-385; SER-397; THR-402; SER-472; SER-496; SER-502; SER-512; SER-531; THR-566; SER-578; SER-658 AND SER-690;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    19. 19.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    20. 20.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-196; SER-198; SER-222; SER-268; SER-285; SER-290; SER-385; SER-397; THR-494; SER-496; SER-512; SER-531; SER-658; SER-660 AND SER-760;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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