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Index > Protein center > NGFRAP1(Gene name) > Human
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  • NGFRAP1 (Gene name),
  • Protein BEX3 (Protein name ),  BEX3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NGFRAP1(BEX3;DXS6984E;NADE);
    Protein name:
    Protein BEX3;
    Alternative:
    Nerve growth factor receptor-associated protein 1;Brain-expressed X-linked protein 3;p75NTR-associated cell death executor;Ovarian granulosa cell 13.0 kDa protein HGR74;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to the DEATH domain of p75NTR/NGFR.
    Function:
    May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
    Subcellular Location:
    Nucleus Cytoplasm Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.
    Protein Attributes:
    Sequence length:
    111
    Sequence:
    50:
    MANIHQENEE | MEQPMQNGEE | DRPLGGGEGH | QPAGNRRGQA | RRLAPNFRWA | 
    100:
    IPNRQINDGM | GGDGDDMEIF | MEEMREIRRK | LRELQLRNCL | RILMGELSNH | 
    111:
    HDHHDEFCLM | P
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein BEX3
    ELISA Kit for Human Protein BEX3
    ELISA Kit for Human Protein BEX3
    ELISA Kit for Human Protein BEX3
    CLIA Kit for Human Protein BEX3
    CLIA Kit for Human Protein BEX3
    CLIA Kit for Human Protein BEX3
    CLIA Kit for Human Protein BEX3
    Polyclonal Antibody for Human Protein BEX3
    Polyclonal Antibody for Human Protein BEX3
    Polyclonal Antibody for Human Protein BEX3
    Polyclonal Antibody for Human Protein BEX3
    Monoclonal Antibody for Human Protein BEX3
    Monoclonal Antibody for Human Protein BEX3
    Monoclonal Antibody for Human Protein BEX3
    Monoclonal Antibody for Human Protein BEX3
    Protein for Human Protein BEX3
    Protein for Human Protein BEX3
    Protein for Human Protein BEX3
    Protein for Human Protein BEX3

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    Precision
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    Linearity
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    References
    1. 1.
      "Characterization of three abundant mRNAs from human ovarian granulosa cells."
      Rapp G. , Freudenstein J. , Klaudiny J. , Mucha J. , Wempe F. , Zimmer M. , Scheit K.H.
      DNA Cell Biol.9:479-485(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Ovary.
    2. 2.
      "NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR."
      Mukai J. , Hachiya T. , Shoji-Hoshino S. , Kimura M.T. , Nadano D. , Suvanto P. , Hanaoka T. , Li Y. , Irie S. , Greene L.A. , Sato T.-A.
      J. Biol. Chem.275:17566-17570(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CHARACTERIZATION
    3. 3.
      "Characterization of the Bex gene family in humans, mice, and rats."
      Alvarez E. , Zhou W. , Witta S.E. , Freed C.R.
      Gene357:18-28(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Cerebellum.
    5. 5.
      "A comparative gene expression profile of the whole eye from human, mouse, and guinea pig."
      Zhou X. , Wang W. , Lu F. , Hu S. , Jiang L. , Yan D. , Zhang X. , Yu X. , Yu J. , Qu J.
      Mol. Vis.13:2214-2221(2007)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Eye.
    6. 6.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Eye.
    9. 9.
      "Theoretical model for p75NTR-associated cell death executor."
      Arunkumar S.
      Submitted (2005-01) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 1-111
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