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Index > Protein center > BFAR(Gene name) > Human
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  • BFAR (Gene name),
  • Bifunctional apoptosis regulator (Protein name ),  BFAR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BFAR(BAR;RNF47);
    Protein name:
    Bifunctional apoptosis regulator;
    Alternative:
    RING finger protein 47;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CASP8, BCL2 and BCL2L1 through SAM domain and also with HIP1, IFT57, ESRRBL1 and BCAP31.
    Function:
    Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    450
    Sequence:
    50:
    MEEPQKSYVN | TMDLERDEPL | KSTGPQISVS | EFSCHCCYDI | LVNPTTLNCG | 
    100:
    HSFCRHCLAL | WWASSKKTEC | PECREKWEGF | PKVSILLRDA | IEKLFPDAIR | 
    150:
    LRFEDIQQNN | DIVQSLAAFQ | KYGNDQIPLA | PNTGRANQQM | GGGFFSGVLT | 
    200:
    ALTGVAVVLL | VYHWSSRESE | HDLLVHKAVA | KWTAEEVVLW | LEQLGPWASL | 
    250:
    YRERFLSERV | NGRLLLTLTE | EEFSKTPYTI | ENSSHRRAIL | MELERVKALG | 
    300:
    VKPPQNLWEY | KAVNPGRSLF | LLYALKSSPR | LSLLYLYLFD | YTDTFLPFIH | 
    350:
    TICPLQEDSS | GEDIVTKLLD | LKEPTWKQWR | EFLVKYSFLP | YQLIAEFAWD | 
    400:
    WLEVHYWTSR | FLIINAMLLS | VLELFSFWRI | WSRSELKTVP | QRMWSHFWKV | 
    450:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Bifunctional apoptosis regulator
    ELISA Kit for Human Bifunctional apoptosis regulator
    ELISA Kit for Human Bifunctional apoptosis regulator
    CLIA Kit for Human Bifunctional apoptosis regulator
    CLIA Kit for Human Bifunctional apoptosis regulator
    CLIA Kit for Human Bifunctional apoptosis regulator
    Polyclonal Antibody for Human Bifunctional apoptosis regulator
    Polyclonal Antibody for Human Bifunctional apoptosis regulator
    Polyclonal Antibody for Human Bifunctional apoptosis regulator
    Monoclonal Antibody for Human Bifunctional apoptosis regulator
    Monoclonal Antibody for Human Bifunctional apoptosis regulator
    Monoclonal Antibody for Human Bifunctional apoptosis regulator
    Protein for Human Bifunctional apoptosis regulator
    Protein for Human Bifunctional apoptosis regulator
    Protein for Human Bifunctional apoptosis regulator

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "BAR: an apoptosis regulator at the intersection of caspases and Bcl-2 family proteins."
      Zhang H. , Xu Q. , Krajewski S. , Krajewska M. , Xie Z. , Fuess S. , Kitada S. , Pawlowski K. , Godzik A. , Reed J.C.
      Proc. Natl. Acad. Sci. U.S.A.97:2597-2602(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH CASP8; BCL2 AND BCL2L1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Hepatoma.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    6. 6.
      "Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways."
      Roth W. , Kermer P. , Krajewska M. , Welsh K. , Davis S. , Krajewski S. , Reed J.C.
      Cell Death Differ.10:1178-1187(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH IFT57; HIP1; ESRRBL1 AND BCAP31;TISSUE SPECIFICITY
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