BIRC5 ELISA Kit for Human(Homo sapiens) | EIAab.comBIRC5 ELISA Kit for Human(Homo sapiens)

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BIRC5 (Gene name),

Baculoviral IAP repeat-containing protein 5 (Protein name ), BIRC5_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BIRC5(API4;IAP4);

Protein name:

Baculoviral IAP repeat-containing protein 5;

Alternative:

Apoptosis inhibitor survivin;Apoptosis inhibitor 4;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer or homodimer. Exist as a homodimer in the apo state and as a monomer in the CPC-bound state. When phosphorylated, interacts with HBXIP; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently. Component of the chromosomal passenger complex (CPC) composed of at least BIRC5/survivin, CDCA8/borealin, INCENP, AURKB and AURKC. Interacts with JTB. Interacts with CDCA8 and INCENP; interaction is direct. Interacts with EVI5. Interacts with GTP-bound RAN in both the S and M phases of the cell cycle. Interacts with USP9X. Interacts with tubulin.

Function:

Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Inhibitor of caspase-3 and caspase-7. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform.

Subcellular Location:

Cytoplasm Nucleus Chromosome Chromosome centromere Cytoplasm cytoskeleton spindle Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.

Protein Attributes:

Sequence length:

142

Sequence:

50:

100:

142:

FLKLDRERAK | NKIAKETNNK | KKEFEETAEK | VRRAIEQLAA | MD

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

MIM:

603352

String:

O15392

KEGG:

hsa:332

UniGene:

Hs.744872

Pfam:

PF00653

STRING:

9606.ENSP00000301633

UniGene:

Hs.514527

SMR:

O15392

Uniprot:

O15392

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045h

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045m

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045b

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045p

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045d

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 5

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E2045r

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96T

CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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U2045d

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CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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U2045b

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CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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U2045p

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CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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U2045r

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CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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U2045m

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CLIA Kit for Human Baculoviral IAP repeat-containing protein 5

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Polyclonal Antibody for Human Baculoviral IAP repeat-containing protein 5

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P2045Rb-r

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Polyclonal Antibody for Human Baculoviral IAP repeat-containing protein 5

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Polyclonal Antibody for Human Baculoviral IAP repeat-containing protein 5

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Monoclonal Antibody for Human Baculoviral IAP repeat-containing protein 5

Protein for Human Baculoviral IAP repeat-containing protein 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma."
Ambrosini G. , Adida C. , Altieri D.C.
Nat. Med.3:917-921(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
2.

"Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties."
Mahotka C. , Wenzel M. , Springer E. , Gabbert H.E. , Gerharz C.D.
Cancer Res.59:6097-6102(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);FUNCTION;TISSUE SPECIFICITY
3.

"Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype."
Uren A.G. , Wong L. , Pakusch M. , Fowler K.J. , Burrows F.J. , Vaux D.L. , Choo K.H.
Curr. Biol.10:1319-1328(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION
4.

"Identification of a novel splice variant of the human anti-apoptosis gene survivin."
Badran A. , Yoshida A. , Ishikawa K. , Goi T. , Yamaguchi A. , Ueda T. , Inuzuka M.
Biochem. Biophys. Res. Commun.314:902-907(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);TISSUE SPECIFICITY
tissue: Myeloid leukemia cell.
5.

"Molecular cloning and bioinformatics analysis of a novel spliced variant of survivin from human breast cancer cells."
Zheng W. , Ma X. , Wei D. , Wang T. , Ma Y. , Yang S.
DNA Seq.16:321-328(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5);TISSUE SPECIFICITY
tissue: Mammary cancer.
6.

"An isoform of survivin (survivin-beta) which has 23 amino acids insertion into the BIR domain."
Kageyama H. , Islam A. , Takayasu H. , Nakagawara A.
Submitted (1999-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Neuroblastoma.
7.

"Survivin 2 alpha: a novel survivin splice variant expressed in human malignancies."
Caldas H. , Honsey L.E. , Altura R.A.
Submitted (2005-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7)
8.

"Identification of a novel survivin splicing variant 3alpha in acute myeloid leukemia."
Vietri M.T. , Cioffi M. , Sessa M. , Sica V. , Molinari A.M.
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6)
tissue: Myeloid leukemia cell.
9.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
10.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
11.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
12.

NIEHS SNPs program
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
13.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLU-129
14.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
15.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Lung.
tissue: Mammary gland.
tissue: Muscle.
16.

"Control of apoptosis and mitotic spindle checkpoint by survivin."
Li F. , Ambrosini G. , Chu E.Y. , Plescia J. , Tognin S. , Marchisio P.C. , Altieri D.C.
Nature396:580-584(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
17.

"Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin."
O'Connor D.S. , Grossman D. , Plescia J. , Li F. , Zhang H. , Villa A. , Tognin S. , Marchisio P.C. , Altieri D.C.
Proc. Natl. Acad. Sci. U.S.A.97:13103-13107(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-34
18.

"HBXIP functions as a cofactor of survivin in apoptosis suppression."
Marusawa H. , Matsuzawa S. , Welsh K. , Zou H. , Armstrong R. , Tamm I. , Reed J.C.
EMBO J.22:2729-2740(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN APOPTOSIS SUPPRESSION;INTERACTION WITH LAMTOR5/HBXIP;MUTAGENESIS OF THR-34;SUBCELLULAR LOCATION
19.

"Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo."
Wheatley S.P. , Henzing A.J. , Dodson H. , Khaled W. , Earnshaw W.C.
J. Biol. Chem.279:5655-5660(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INCENP;SUBCELLULAR LOCATION;PHOSPHORYLATION AT THR-117;MUTAGENESIS OF THR-117
20.

"Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle."
Gassmann R. , Carvalho A. , Henzing A.J. , Ruchaud S. , Hudson D.F. , Honda R. , Nigg E.A. , Gerloff D.L. , Earnshaw W.C.
J. Cell Biol.166:179-191(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDCA8
21.

"cIAP1 Localizes to the nuclear compartment and modulates the cell cycle."
Samuel T. , Okada K. , Hyer M. , Welsh K. , Zapata J.M. , Reed J.C.
Cancer Res.65:210-218(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH BIRC2/C-IAP1
22.

"Survivin: a protein with dual roles in mitosis and apoptosis."
Wheatley S.P. , McNeish I.A.
Int. Rev. Cytol.247:35-88(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
23.

"Chromosome alignment and segregation regulated by ubiquitination of survivin."
Vong Q.P. , Cao K. , Li H.Y. , Iglesias P.A. , Zheng Y.
Science310:1499-1504(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH USP9X;SUBCELLULAR LOCATION;UBIQUITINATION;MUTAGENESIS OF LYS-23; LYS-62; LYS-78 AND LYS-79
24.

"Survivin mutant (Surv-DD70, 71AA) disrupts the interaction of Survivin with Aurora B and causes multinucleation in HeLa cells."
Cao L. , Yan X. , Wu Y. , Hu H. , Li Q. , Zhou T. , Jiang S. , Yu L.
Biochem. Biophys. Res. Commun.346:400-407(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASP-70; ASP-71 AND 70-ASP--ASP-71
25.

"Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody."
Vader G. , Kauw J.J.W. , Medema R.H. , Lens S.M.A.
EMBO Rep.7:85-92(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDCA8
26.

"Borealin/Dasra B is a cell cycle-regulated chromosomal passenger protein and its nuclear accumulation is linked to poor prognosis for human gastric cancer."
Chang J.-L. , Chen T.-H. , Wang C.-F. , Chiang Y.-H. , Huang Y.-L. , Wong F.-H. , Chou C.-K. , Chen C.-M.
Exp. Cell Res.312:962-973(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDCA8
27.

"EVI5 protein associates with the INCENP-aurora B kinase-survivin chromosomal passenger complex and is involved in the completion of cytokinesis."
Faitar S.L. , Sossey-Alaoui K. , Ranalli T.A. , Cowell J.K.
Exp. Cell Res.312:2325-2335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EVI5
28.

"Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis."
Noton E.A. , Colnaghi R. , Tate S. , Starck C. , Carvalho A. , Ko Ferrigno P. , Wheatley S.P.
J. Biol. Chem.281:1286-1295(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CDCA8
29.

"Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres."
Lens S.M.A. , Rodriguez J.A. , Vader G. , Span S.W. , Giaccone G. , Medema R.H.
Mol. Biol. Cell17:1897-1909(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDCA8
30.

"Final stages of cytokinesis and midbody ring formation are controlled by BRUCE."
Pohl C. , Jentsch S.
Cell132:832-845(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BIRC6/BRUCE
31.

"Cartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteins."
Gagarina V. , Carlberg A.L. , Pereira-Mouries L. , Hall D.J.
J. Biol. Chem.283:648-659(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
32.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-34;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
33.

"A survivin-ran complex regulates spindle formation in tumor cells."
Xia F. , Canovas P.M. , Guadagno T.M. , Altieri D.C.
Mol. Cell. Biol.28:5299-5311(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAN; AURKB AND CDCA8;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;MUTAGENESIS OF GLU-65
34.

"Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity."
Wang H. , Holloway M.P. , Ma L. , Cooper Z.A. , Riolo M. , Samkari A. , Elenitoba-Johnson K.S. , Chin Y.E. , Altura R.A.
J. Biol. Chem.285:36129-36137(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH STAT3 AND XPO1/CRM1;ACETYLATION AT LYS-23; LYS-90; LYS-110; LYS-112; LYS-115; LYS-121 AND LYS-129;MUTAGENESIS OF LYS-129;CHARACTERIZATION OF VARIANT GLU-129
35.

"Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro."
Barrett R.M. , Colnaghi R. , Wheatley S.P.
Cell Cycle10:538-548(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-48;MUTAGENESIS OF THR-48
36.

"PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins."
Platica M. , Ionescu A. , Ivan E. , Holland J.F. , Mandeli J. , Platica O.
Int. J. Oncol.38:777-785(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JTB
37.

"Survivin monomer plays an essential role in apoptosis regulation."
Pavlyukov M.S. , Antipova N.V. , Balashova M.V. , Vinogradova T.V. , Kopantzev E.P. , Shakhparonov M.I.
J. Biol. Chem.286:23296-23307(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;INTERACTION WITH XIAP/BIRC4 AND DIABLO/SMAC
38.

"CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity."
Li Z. , Pei X.H. , Yan J. , Yan F. , Cappell K.M. , Whitehurst A.W. , Xiong Y.
Mol. Cell54:805-819(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION
39.

"Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions."
Chantalat L. , Skoufias D.A. , Kleman J.P. , Jung B. , Dideberg O. , Margolis R.L.
Mol. Cell6:183-189(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.71 ANGSTROMS) OF ISOFORM 1
40.

"Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement."
Verdecia M.A. , Huang H. , Dutil E. , Kaiser D.A. , Hunter T. , Noel J.P.
Nat. Struct. Biol.7:602-608(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.58 ANGSTROMS) OF ISOFORM 1
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"Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together."
Jeyaprakash A.A. , Klein U.R. , Lindner D. , Ebert J. , Nigg E.A. , Conti E.
Cell131:271-285(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) IN COMPLEX WITH ZINC IONS;SUBUNIT;INTERACTION WITH CDCA8 AND INCENP
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"Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation."
Bourhis E. , Lingel A. , Phung Q. , Fairbrother W.J. , Cochran A.G.
Biochemistry48:6783-6793(2009) [PubMed] [Europe PMC] [Abstract]

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