Bloc1s5 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comBloc1s5 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Bloc1s5(Gene name) > Rat

Bloc1s5 (Gene name),

Biogenesis of lysosome-related organelles complex 1 subunit 5 (Protein name ), BL1S5_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Bloc1s5(Mu;Muted);

Protein name:

Biogenesis of lysosome-related organelles complex 1 subunit 5(BLOC-1 subunit 5);

Alternative:

Protein Muted homolog;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Octamer composed of one copy each BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6, DTNBP1/BLOC1S7 and SNAPIN/BLOC1S8. The BLOC-1 complex associates with the AP-3 protein complex and membrane protein cargos. Interacts with BLOC1S4, BLOC1S6, DTNBP1/BLOC1S7 and PI4K2A (By similarity). Component of the biogenesis of lysosome-related organelles complex 1 (BLOC-1) composed of BLOC1S1, BLOC1S2, BLOC1S3, BLOC1S4, BLOC1S5, BLOC1S6, DTNBP1/BLOC1S7 and SNAPIN/BLOC1S8.

Function:

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

187

Sequence:

50:

100:

150:

187:

GQPQRRAEVD | AEHRKAMERL | REQYAAMEKD | LAKFSTF

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Rn.1373

Pfam:

PF14942

KEGG:

rno:306868

STRING:

10116.ENSRNOP00000022108

Uniprot:

B2GV52

FOR

ELISA Kit for Rat BLOC-1 subunit 5

CLIA Kit for Rat BLOC-1 subunit 5

Polyclonal Antibody for Rat BLOC-1 subunit 5

Monoclonal Antibody for Rat BLOC-1 subunit 5

Protein for Rat BLOC-1 subunit 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Heart.
3.

"BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes."
Salazar G. , Craige B. , Styers M.L. , Newell-Litwa K.A. , Doucette M.M. , Wainer B.H. , Falcon-Perez J.M. , Dell'Angelica E.C. , Peden A.A. , Werner E. , Faundez V.
Mol. Biol. Cell17:4014-4026(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE BLOC-1 COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY

Product Feedback Wall

* Email:
*Comments: