Bmp4 ELISA Kit for Mouse(Mus musculus) | EIAab.comBmp4 ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Bmp4(Gene name) > Mouse

Bmp4 (Gene name),

Bone morphogenetic protein 4 (Protein name ), BMP4_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Bmp4(Bmp-4;Dvr-4);

Protein name:

Bone morphogenetic protein 4(BMP-4);

Alternative:

Bone morphogenetic protein 2B(BMP-2B);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer; disulfide-linked (By similarity). Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC. Part of a complex consisting of TWSG1 and CHRD.

Function:

Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

408

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

408:

VVEGCGCR

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

mmu:12159

Pfam:

PF00019

STRING:

10090.ENSMUSP00000098242

SMR:

P21275

UniGene:

Mm.6813

String:

P21275

Uniprot:

P21275

FOR

ELISA Kit for Mouse BMP-4

Cat.:

E0014h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse BMP-4

Cat.:

E0014m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse BMP-4

Cat.:

E0014r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse BMP-4

MSDS:

Please sign in first.

ELISA Kit for Mouse BMP-4

Cat.:

E0014b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse BMP-4

Cat.:

E0014c

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse BMP-4

Cat.:

U0014c

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse BMP-4

Cat.:

U0014b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse BMP-4

MSDS:

Please sign in first.

CLIA Kit for Mouse BMP-4

Cat.:

U0014r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse BMP-4

Cat.:

U0014m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse BMP-4

Cat.:

U0014h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

Polyclonal Antibody for Mouse BMP-4

Cat.:

P0014Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse BMP-4

Cat.:

P0014Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse BMP-4

Cat.:

P0014Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse BMP-4

Protein for Mouse BMP-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.4%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.9%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of BMP4 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	99	96-102
Plasma	98	94-100

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of BMP4 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	96-100%	98-101%	94-99%	96-100%
EDTA plasma(n=5)	95-99%	98-103%	100-103%	102-106%
heparin plasma(n=5)	96-101%	98-100%	95-103%	101-105%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Nucleotide sequence of the mouse bone morphogenetic protein-4 (BMP-4) cDNA."
Dickinson M.E. , van der Meer-De Jong R. , Hogan B.L.M.
Submitted (1992-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Murine bone morphogenetic protein-4 gene: existence of multiple promoters and exons for the 5'-untranslated region."
Kurihara T. , Kitamura K. , Takaoka K. , Nakazato H.
Biochem. Biophys. Res. Commun.192:1049-1056(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Gene cloning and expression of a bone morphogenetic protein derived from a murine osteosarcoma."
Takaoka K. , Yoshikawa H. , Hasimoto J. , Masuhara K. , Miyamoto S. , Suzuki S. , Ono K. , Matsui M. , Oikawa S. , Tsuruoka N.
Clin. Orthop. Relat. Res.294:344-352(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor."
Feng J.Q. , Chen D. , Cooney A.J. , Tsai M. , Harris M.A. , Tsai S.Y. , Feng M. , Mundy G.R. , Harris S.E.
J. Biol. Chem.270:28364-28373(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129/Sv.
tissue: Liver.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C3H/He.
strain: FVB/N.
tissue: Colon.
tissue: Osteoblast.
tissue: Salivary gland.
6.

"Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci."
Dickinson M.E. , Kobrin M.S. , Silan C.M. , Kingsley D.M. , Justice M.J. , Miller D.A. , Ceci J.D. , Lock L.F. , Lee A. , Buchberg A.M. , Siracusa L.D. , Lyons K.M. , Derynck R. , Hogan B.L.M. , Copeland N.G. , Jenkins N.A.
Genomics6:505-520(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 241-408
7.

"Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling."
Scott I.C. , Blitz I.L. , Pappano W.N. , Maas S.A. , Cho K.W.Y. , Greenspan D.S.
Nature410:475-478(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TWSG1 AND CHRD
8.

"Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot."
Laurikkala J. , Kassai Y. , Pakkasjaervi L. , Thesleff I. , Itoh N.
Dev. Biol.264:91-105(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SOSTDC1
9.

"Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling."
Tocharus J. , Tsuchiya A. , Kajikawa M. , Ueta Y. , Oka C. , Kawaichi M.
Dev. Growth Differ.46:257-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTRA3;FUNCTION
10.

"HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins."
Oka C. , Tsujimoto R. , Kajikawa M. , Koshiba-Takeuchi K. , Ina J. , Yano M. , Tsuchiya A. , Ueta Y. , Soma A. , Kanda H. , Matsumoto M. , Kawaichi M.
Development131:1041-1053(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTRA1;FUNCTION
11.

"Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation."
Sudo S. , Avsian-Kretchmer O. , Wang L.S. , Hsueh A.J.
J. Biol. Chem.279:23134-23141(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GREM2
12.

"DRAGON, a bone morphogenetic protein co-receptor."
Samad T.A. , Rebbapragada A. , Bell E. , Zhang Y. , Sidis Y. , Jeong S.-J. , Campagna J.A. , Perusini S. , Fabrizio D.A. , Schneyer A.L. , Lin H.Y. , Brivanlou A.H. , Attisano L. , Woolf C.J.
J. Biol. Chem.280:14122-14129(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMB
13.

"Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor."
Babitt J.L. , Zhang Y. , Samad T.A. , Xia Y. , Tang J. , Campagna J.A. , Schneyer A.L. , Woolf C.J. , Lin H.Y.
J. Biol. Chem.280:29820-29827(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA
14.

"Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression."
Babitt J.L. , Huang F.W. , Wrighting D.M. , Xia Y. , Sidis Y. , Samad T.A. , Campagna J.A. , Chung R.T. , Schneyer A.L. , Woolf C.J. , Andrews N.C. , Lin H.Y.
Nat. Genet.38:531-539(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMC
15.

"BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction."
Hens J.R. , Dann P. , Zhang J.P. , Harris S. , Robinson G.W. , Wysolmerski J.
Development134:1221-1230(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
16.

"Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4."
Xia Y. , Yu P.B. , Sidis Y. , Beppu H. , Bloch K.D. , Schneyer A.L. , Lin H.Y.
J. Biol. Chem.282:18129-18140(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA

Product Feedback Wall

* Email:
*Comments: