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Index > Protein center > Bmpr2(Gene name) > Mouse
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  • Bmpr2 (Gene name),
  • Bone morphogenetic protein receptor type-2 (Protein name ),  BMPR2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Bmpr2;
    Protein name:
    Bone morphogenetic protein receptor type-2(BMP type-2 receptor;BMPR-2);
    Alternative:
    Bone morphogenetic protein receptor type II(BMP type II receptor;BMPR-II);BRK-3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1038
    Sequence:
    50:
    MTSSLHRPFR | VPWLLWAVLL | VSTTAASQNQ | ERLCAFKDPY | QQDLGIGESR | 
    100:
    ISHENGTILC | SKGSTCYGLW | EKSKGDINLV | KQGCWSHIGD | PQECHYEECV | 
    150:
    VTTTPPSIQN | GTYRFCCCST | DLCNVNFTEN | FPPPDTTPLS | PPHSFNRDET | 
    200:
    IIIALASVSV | LAVLIVALCF | GYRMLTGDRK | QGLHSMNMME | AAAAEPSLDL | 
    250:
    DNLKLLELIG | RGRYGAVYKG | SLDERPVAVK | VFSFANRQNF | INEKNIYRVP | 
    300:
    LMEHDNIARF | IVGDERLTAD | GRMEYLLVME | YYPNGSLCKY | LSLHTSDWVS | 
    350:
    SCRLAHSVTR | GLAYLHTELP | RGDHYKPAIS | HRDLNSRNVL | VKNDGACVIS | 
    400:
    DFGLSMRLTG | NRLVRPGEED | NAAISEVGTI | RYMAPEVLEG | AVNLRDCESA | 
    450:
    LKQVDMYALG | LIYWEVFMRC | TDLFPGESVP | DYQMAFQTEV | GNHPTFEDMQ | 
    500:
    VLVSREKQRP | KFPEAWKENS | LAVRSLKETI | EDCWDQDAEA | RLTAQCAEER | 
    550:
    MAELMMIWER | NKSVSPTVNP | MSTAMQNERN | LSHNRRVPKI | GPYPDYSSSS | 
    600:
    YIEDSIHHTD | SIVKNISSEH | SMSSTPLTIG | EKNRNSINYE | RQQAQARIPS | 
    650:
    PETSVTSLST | NTTTTNTTGL | TPSTGMTTIS | EMPYPDETHL | HATNVAQSIG | 
    700:
    PTPVCLQLTE | EDLETNKLDP | KEVDKNLKES | SDENLMEHSL | KQFSGPDPLS | 
    750:
    STSSSLLYPL | IKLAVEVTGQ | QDFTQAANGQ | ACLIPDVPPA | QIYPLPKQQN | 
    800:
    LPKRPTSLPL | NTKNSTKEPR | LKFGNKHKSN | LKQVETGVAK | MNTINAAEPH | 
    850:
    VVTVTMNGVA | GRSHNVNSHA | ATTQYANGAV | PAGQAANIVA | HRSQEMLQNQ | 
    900:
    FIGEDTRLNI | NSSPDEHEPL | LRREQQAGHD | EGVLDRLVDR | RERPLEGGRT | 
    950:
    NSNNNNSNPC | SEQDILTQGV | TSTAADPGPS | KPRRAQRPNS | LDLSATNILD | 
    1000:
    GSSIQIGEST | QDGKSGSGEK | IKRRVKTPYS | LKRWRPSTWV | ISTEPLDCEV | 
    1038:
    NNNGSDRAVH | SKSSTAVYLA | EGGTATTTVS | KDIGMNCL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse BMP type-2 receptor
    Cat.:
    E0016h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BMP type-2 receptor
    Cat.:
    E0016m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BMP type-2 receptor
    Cat.:
    U0016m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BMP type-2 receptor
    Cat.:
    U0016h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse BMP type-2 receptor
    Cat.:
    P0016Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse BMP type-2 receptor
    Cat.:
    P0016Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse BMP type-2 receptor
    Monoclonal Antibody for Mouse BMP type-2 receptor
    Protein for Mouse BMP type-2 receptor
    Protein for Mouse BMP type-2 receptor

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    Linearity
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    References
    1. 1.
      "cDNA cloning and genomic organization of the mouse BMP type II receptor."
      Beppu H. , Minowa O. , Miyazono K. , Kawabata M.
      Biochem. Biophys. Res. Commun.235:499-504(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Identification of BMP receptor complexes with differential signaling properties and ligand binding profiles."
      Whitaker G.B. , Koenig B.B. , Ting J. , Tiesman J.P. , Limberg A.L. , Grant R.A. , Begley K.B. , Rosenbaum J.S.
      Submitted (1997-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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