Brdt ELISA Kit for Mouse(Mus musculus) | EIAab.comBrdt ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Brdt(Gene name) > Mouse

Brdt (Gene name),

Bromodomain testis-specific protein (Protein name ), BRDT_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Brdt(Fsrg3);

Protein name:

Bromodomain testis-specific protein;

Alternative:

RING3-like protein;Bromodomain-containing female sterile homeotic-like protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with histone H4 acetylated N-terminus.

Function:

May play a role in the transcriptional regulation of spermatogenesis. Seems to have a structural ATP-independent role in the reorganization of acetylated chromatin.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

956

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

956:

FENNFD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:114642

Pfam:

PF00439

UniGene:

Mm.182836

STRING:

10090.ENSMUSP00000108297

SMR:

Q91Y44

Uniprot:

Q91Y44

FOR

ELISA Kit for Mouse Bromodomain testis-specific protein

CLIA Kit for Mouse Bromodomain testis-specific protein

Polyclonal Antibody for Mouse Bromodomain testis-specific protein

Monoclonal Antibody for Mouse Bromodomain testis-specific protein

Protein for Mouse Bromodomain testis-specific protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testis."
Shang E. , Salazar G. , Crowley T.E. , Wang X. , Lopez R.A. , Wang X. , Wolgemuth D.J.
Gene Expr. Patterns4:513-519(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue: Testis.
2.

"The Brd paralogous genes: testis-specific expression of the splicing variants."
Taniguchi Y.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Testis.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein."
Pivot-Pajot C. , Caron C. , Govin J. , Vion A. , Rousseaux S. , Khochbin S.
Mol. Cell. Biol.23:5354-5365(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HISTONE H4;MUTAGENESIS OF 50-PRO-PHE-51; VAL-55; 293-PRO-PHE-294 AND VAL-298
6.

"The first bromodomain of Brdt, a testis-specific member of the BET sub-family of double-bromodomain-containing proteins, is essential for male germ cell differentiation."
Shang E. , Nickerson H.D. , Wen D. , Wang X. , Wolgemuth D.J.
Development134:3507-3515(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
7.

"Bromodomain testis-specific protein is expressed in mouse oocyte and evolves faster than its ubiquitously expressed paralogs BRD2, -3, and -4."
Paillisson A. , Levasseur A. , Gouret P. , Callebaut I. , Bontoux M. , Pontarotti P. , Monget P.
Genomics89:215-223(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background."
Berkovits B.D. , Wolgemuth D.J.
Dev. Biol.360:358-368(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE
9.

"Small-molecule inhibition of BRDT for male contraception."
Matzuk M.M. , McKeown M.R. , Filippakopoulos P. , Li Q. , Ma L. , Agno J.E. , Lemieux M.E. , Picaud S. , Yu R.N. , Qi J. , Knapp S. , Bradner J.E.
Cell150:673-684(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"Bromodomain-dependent stage-specific male genome programming by Brdt."
Gaucher J. , Boussouar F. , Montellier E. , Curtet S. , Buchou T. , Bertrand S. , Hery P. , Jounier S. , Depaux A. , Vitte A.L. , Guardiola P. , Pernet K. , Debernardi A. , Lopez F. , Holota H. , Imbert J. , Wolgemuth D.J. , Gerard M. , more...
EMBO J.31:3809-3820(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE;DISRUPTION PHENOTYPE;INTERACTION WITH CDK9 AND CCNT1
11.

"The testis-specific double bromodomain-containing protein BRDT forms a complex with multiple spliceosome components and is required for mRNA splicing and 3'-UTR truncation in round spermatids."
Berkovits B.D. , Wang L. , Guarnieri P. , Wolgemuth D.J.
Nucleic Acids Res.40:7162-7175(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SRSF2; DDX5; HNRNPK AND TARDBP
12.

"Cooperative binding of two acetylation marks on a histone tail by a single bromodomain."
Moriniere J. , Rousseaux S. , Steuerwald U. , Soler-Lopez M. , Curtet S. , Vitte A.L. , Govin J. , Gaucher J. , Sadoul K. , Hart D.J. , Krijgsveld J. , Khochbin S. , Muller C.W. , Petosa C.
Nature461:664-668(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 17-136 AND 257-382 IN COMPLEX WITH HISTONE H4 PEPTIDE;FUNCTION;SUBUNIT;SUBCELLULAR LOCATION

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