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Index > Protein center > BRINP1(Gene name) > Human
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  • BRINP1 (Gene name),
  • BMP/retinoic acid-inducible neural-specific protein 1 (Protein name ),  BRNP1_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    BRINP1(IB3089A;DBC1;DBCCR1;FAM5A);
    Protein name:
    BMP/retinoic acid-inducible neural-specific protein 1;
    Alternative:
    Deleted in bladder cancer protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    761
    Sequence:
    50:
    MNWRFVELLY | FLFIWGRISV | QPSHQEPAGT | DQHVSKEFDW | LISDRGPFHH | 
    100:
    SRSYLSFVER | HRQGFTTRYK | IYREFARWKV | RNTAIERRDL | VRHPVPLMPE | 
    150:
    FQRSIRLLGR | RPTTQQFIDT | IIKKYGTHLL | ISATLGGEEA | LTMYMDKSRL | 
    200:
    DRKSGNATQS | VEALHQLASS | YFVDRDGTMR | RLHEIQISTG | AIKVTETRTG | 
    250:
    PLGCNSYDNL | DSVSSVLLQS | TESKLHLQGL | QIIFPQYLQE | KFVQSALSYI | 
    300:
    MCNGEGEYLC | QNSQCRCQCA | EEFPQCNCPI | TDIQIMEYTL | ANMAKSWAEA | 
    350:
    YKDLENSDEF | KSFMKRLPSN | HFLTIGSIHQ | HWGNDWDLQN | RYKLLQSATE | 
    400:
    AQRQKIQRTA | RKLFGLSVRC | RHNPNHQLPR | ERTIQQWLAR | VQSLLYCNEN | 
    450:
    GFWGTFLESQ | RSCVCHGSTT | LCQRPIPCVI | GGNNSCAMCS | LANISLCGSC | 
    500:
    NKGYKLYRGR | CEPQNVDSER | SEQFISFETD | LDFQDLELKY | LLQKMDSRLY | 
    550:
    VHTTFISNEI | RLDTFFDPRW | RKRMSLTLKS | NKNRMDFIHM | VIGMSMRICQ | 
    600:
    MRNSSLDPMF | FVYVNPFSGS | HSEGWNMPFG | EFGYPRWEKI | RLQNSQCYNW | 
    650:
    TLLLGNRWKT | FFETVHIYLR | SRTRLPTLLR | NETGQGPVDL | SDPSKRQFYI | 
    700:
    KISDVQVFGY | SLRFNADLLR | SAVQQVNQSY | TQGGQFYSSS | SVMLLLLDIR | 
    750:
    DRINRLAPPV | APGKPQLDLF | SCMLKHRLKL | TNSEIIRVNH | ALDLYNTEIL | 
    761:
    KQSDQMTAKL | C
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    ELISA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    ELISA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    ELISA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    ELISA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    CLIA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    CLIA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    CLIA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    CLIA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    CLIA Kit for Human BMP/retinoic acid-inducible neural-specific protein 1
    Polyclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Polyclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Polyclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Polyclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Polyclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Monoclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Monoclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Monoclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Monoclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Monoclonal Antibody for Human BMP/retinoic acid-inducible neural-specific protein 1
    Protein for Human BMP/retinoic acid-inducible neural-specific protein 1
    Protein for Human BMP/retinoic acid-inducible neural-specific protein 1
    Protein for Human BMP/retinoic acid-inducible neural-specific protein 1
    Protein for Human BMP/retinoic acid-inducible neural-specific protein 1
    Protein for Human BMP/retinoic acid-inducible neural-specific protein 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33."
      Habuchi T. , Luscombe M. , Elder P.A. , Knowles M.A.
      Genomics48:277-288(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-437;TISSUE SPECIFICITY
      tissue: Brain.
    2. 2.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      tissue: Brain.
      tissue: Kidney.
    4. 4.
      "Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1."
      Nishiyama H. , Gill J.H. , Pitt E. , Kennedy W. , Knowles M.A.
      Oncogene20:2956-2964(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;VARIANTS ARG-347; HIS-358 AND THR-437
    5. 5.
      "DBCCR1 mediates death in cultured bladder tumor cells."
      Wright K.O. , Messing E.M. , Reeder J.E.
      Oncogene23:82-90(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "DBC1 re-expression alters the expression of multiple components of the plasminogen pathway."
      Louhelainen J.P. , Hurst C.D. , Pitt E. , Nishiyama H. , Pickett H.A. , Knowles M.A.
      Oncogene25:2409-2419(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] THR-712
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