C1qb ELISA Kit for Rat(Rattus norvegicus) | EIAab.comC1qb ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > C1qb(Gene name) > Rat

C1qb (Gene name),

Complement C1q subcomponent subunit B (Protein name ), C1QB_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

C1qb;

Protein name:

Complement C1q subcomponent subunit B;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the a and B chains, and three of which are disulfide-linked dimers of the C chain. In addition to the major A:B and C:C dimer bands, rat, unlike human C1q, contained minor dimer species.

Function:

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

253

Sequence:

50:

100:

150:

200:

250:

253:

MDV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00386

UniGene:

Rn.6702

STRING:

10116.ENSRNOP00000017060

SMR:

P31721

String:

P31721

KEGG:

rno:29687

Uniprot:

P31721

FOR

ELISA Kit for Rat Complement C1q subcomponent subunit B

CLIA Kit for Rat Complement C1q subcomponent subunit B

Polyclonal Antibody for Rat Complement C1q subcomponent subunit B

Monoclonal Antibody for Rat Complement C1q subcomponent subunit B

Protein for Rat Complement C1q subcomponent subunit B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Follicular dendritic cells, interdigitating cells, and cells of the monocyte-macrophage lineage are the C1q-producing sources in the spleen. Identification of specific cell types by in situ hybridization and immunohistochemical analysis."
Schwaeble W. , Schaefer M.K.-H. , Petry F. , Fink T. , Knebel D. , Weihe E. , Loos M.
J. Immunol.155:4971-4978(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Spleen.
2.

"Rapid isolation and biochemical characterization of rat C1 and C1q."
Wing M.G. , Seilly D.J. , Bridgman D.J. , Harrison R.A.
Mol. Immunol.30:433-440(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 71-79 AND 141-146

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