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Index > Protein center > C1RL(Gene name) > Human
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  • C1RL (Gene name),
  • Complement C1r subcomponent-like protein (Protein name ),  C1RL_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    C1RL(C1RL1;C1RLP;CLSPA);
    Protein name:
    Complement C1r subcomponent-like protein(C1r-LP;C1r-like protein);
    Alternative:
    C1r-like serine protease analog protein(CLSPa);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    487
    Sequence:
    50:
    MPGPRVWGKY | LWRSPHSKGC | PGAMWWLLLW | GVLQACPTRG | SVLLAQELPQ | 
    100:
    QLTSPGYPEP | YGKGQESSTD | IKAPEGFAVR | LVFQDFDLEP | SQDCAGDSVT | 
    150:
    ISFVGSDPSQ | FCGQQGSPLG | RPPGQREFVS | SGRSLRLTFR | TQPSSENKTA | 
    200:
    HLHKGFLALY | QTVAVNYSQP | ISEASRGSEA | INAPGDNPAK | VQNHCQEPYY | 
    250:
    QAAAAGALTC | ATPGTWKDRQ | DGEEVLQCMP | VCGRPVTPIA | QNQTTLGSSR | 
    300:
    AKLGNFPWQA | FTSIHGRGGG | ALLGDRWILT | AAHTIYPKDS | VSLRKNQSVN | 
    350:
    VFLGHTAIDE | MLKLGNHPVH | RVVVHPDYRQ | NESHNFSGDI | ALLELQHSIP | 
    400:
    LGPNVLPVCL | PDNETLYRSG | LLGYVSGFGM | EMGWLTTELK | YSRLPVAPRE | 
    450:
    ACNAWLQKRQ | RPEVFSDNMF | CVGDETQRHS | VCQGDSGSVY | VVWDNHAHHW | 
    487:
    VATGIVSWGI | GCGEGYDFYT | KVLSYVDWIK | GVMNGKN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human C1r-LP
    ELISA Kit for Human C1r-LP
    ELISA Kit for Human C1r-LP
    CLIA Kit for Human C1r-LP
    CLIA Kit for Human C1r-LP
    CLIA Kit for Human C1r-LP
    Polyclonal Antibody for Human C1r-LP
    Polyclonal Antibody for Human C1r-LP
    Polyclonal Antibody for Human C1r-LP
    Monoclonal Antibody for Human C1r-LP
    Monoclonal Antibody for Human C1r-LP
    Monoclonal Antibody for Human C1r-LP
    Protein for Human C1r-LP
    Protein for Human C1r-LP
    Protein for Human C1r-LP

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A novel human dendritic cell-derived C1r-like serine protease analog inhibits complement-mediated cytotoxicity."
      Lin N. , Liu S. , Li N. , Wu P. , An H. , Yu Y. , Wan T. , Cao X.
      Biochem. Biophys. Res. Commun.321:329-336(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION;VARIANT VAL-285
      tissue: Dendritic cell.
    2. 2.
      "A novel human complement-related protein, C1r-like protease (C1r-LP), specifically cleaves pro-C1s."
      Ligoudistianou C. , Xu Y. , Garnier G. , Circolo A. , Volanakis J.E.
      Biochem. J.387:165-173(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
    3. 3.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Prohaptoglobin is proteolytically cleaved in the endoplasmic reticulum by the complement C1r-like protein."
      Wicher K.B. , Fries E.
      Proc. Natl. Acad. Sci. U.S.A.101:14390-14395(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF SER-436
    6. 6.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-166; ASN-242 AND ASN-296
      tissue: Plasma.
    7. 7.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-147; ASN-242 AND ASN-296
      tissue: Liver.
    8. 8.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-242
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