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Index > Protein center > C4bpa(Gene name) > Mouse
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  • C4bpa (Gene name),
  • C4b-binding protein (Protein name ),  C4BPA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    C4bpa(C4bp);
    Protein name:
    C4b-binding protein(C4bp);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homoheptamer; not covalently linked. Mouse lacks the beta chain of C4BP.
    Function:
    Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    469
    Sequence:
    50:
    MCAKQQQTLL | PTRAAHGRLH | RNRDAVAWPF | STLCRVSGPT | LFQMTFTAAL | 
    100:
    WVAVFGKCGP | PPAIPNALPA | SDVNRTDFES | HTTLKYECLP | GYGRGISRMM | 
    150:
    VYCKPSGEWE | ISVSCAKKHC | RNPGYLDNGY | VNGETITFGS | QIEFSCQEGF | 
    200:
    ILVGSSTSSC | EVRGKGVAWS | NPFPECVIVK | CGPPPDISNG | KHSGTEDFYP | 
    250:
    YNHGISYTCD | PGFRLVGSPF | IGCTVVNKTV | PVWSSSPPTC | EKIICSQPNI | 
    300:
    LHGVIVSGYK | ATYTHRDSVR | LACLNGTVLR | GRHVIECQGN | GNWSSLPTCE | 
    350:
    FDCDLPPAIV | NGYYTSMVYS | KITLVTYECD | KGYRLVGKAI | ISCSFSKWKG | 
    400:
    TAPQCKALCQ | KPEVGNGTLS | DEKDQYVESE | NVTIQCDSGF | AMLGSQSISC | 
    450:
    SESGTWYPEV | PRCEQEASED | LKPALTGNKT | MQYVPNSHDV | KMALEIYKLT | 
    469:
    LEVELLQLQI | QKEKHTEAH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C4bp
    Cat.:
    E0761h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse C4bp
    Cat.:
    E0761r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse C4bp
    Cat.:
    E0761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse C4bp
    Cat.:
    E0761b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C4bp
    Cat.:
    U0761m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C4bp
    Cat.:
    U0761h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C4bp
    Cat.:
    U0761b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C4bp
    Cat.:
    U0761r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse C4bp
    Cat.:
    P0761Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C4bp
    Cat.:
    P0761Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C4bp
    Cat.:
    P0761Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C4bp
    Monoclonal Antibody for Mouse C4bp
    Monoclonal Antibody for Mouse C4bp
    Monoclonal Antibody for Mouse C4bp
    Monoclonal Antibody for Mouse C4bp
    Protein for Mouse C4bp
    Protein for Mouse C4bp
    Protein for Mouse C4bp
    Cat.:
    R0761h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse C4bp

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    References
    1. 1.
      "cDNA structure of murine C4b-binding protein, a regulatory component of the serum complement system."
      Kristensen T. , Ogata R.T. , Chung L.P. , Reid K.B.M. , Tack B.F.
      Biochemistry26:4668-4674(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Liver.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
    5. 5.
      "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
      Bernhard O.K. , Kapp E.A. , Simpson R.J.
      J. Proteome Res.6:987-995(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-275
      strain: C57BL/6.
      tissue: Plasma.
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