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Index > Protein center > C5ar2(Gene name) > Mouse
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  • C5ar2 (Gene name),
  • C5a anaphylatoxin chemotactic receptor 2 (Protein name ),  C5AR2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    C5ar2(C5l2;Gpr77);
    Protein name:
    C5a anaphylatoxin chemotactic receptor 2;
    Alternative:
    G-protein coupled receptor 77;Complement component 5a receptor 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with C3 (the anaphylatoxin peptide C3a and the adipogenic hormone ASP); the interaction occurs with higher affinity for ASP, enhancing the phosphorylation and activation of GPR77, recruitment of ARRB2 to the cell surface and endocytosis of GRP77.
    Function:
    Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    344
    Sequence:
    50:
    MMNHTTSEYY | DYEYDHEHYS | DLPDVPVDCP | AGTCFTSDVY | LIVLLVLYAA | 
    100:
    VFLVGVPGNT | LVAWVTWKES | RHRLGASWFL | HLTMADLLCC | VSLPFLAVPI | 
    150:
    AQKGHWPYGA | AGCWLLSSIT | ILSMYASVLL | LTGLSGDLFL | LAFRPSWKGA | 
    200:
    DHRTFGVRVV | QASSWMLGLL | LTVPSAVYRR | LLQEHYPPRL | VCGIDYGGSV | 
    250:
    SAEVAITTVR | FLFGFLGPLV | FMAGCHGILQ | RQMARRHWPL | GTAVVVGFFI | 
    300:
    CWTPYHVLRV | IIAAAPPHSL | LLARVLEAEP | LFNGLALAHS | ALNPIMFLYF | 
    344:
    GRKQLCKSLQ | AACHWALRDP | QDEESAVTKV | SISTSHEMVS | EMPV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    E12838r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    U12838m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Cat.:
    P12838Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Monoclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Monoclonal Antibody for Mouse C5a anaphylatoxin chemotactic receptor 2
    Protein for Mouse C5a anaphylatoxin chemotactic receptor 2
    Protein for Mouse C5a anaphylatoxin chemotactic receptor 2
    Protein for Mouse C5a anaphylatoxin chemotactic receptor 2

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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Lung.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "C5L2 is a functional receptor for acylation-stimulating protein."
      Kalant D. , MacLaren R. , Cui W. , Samanta R. , Monk P.N. , Laporte S.A. , Cianflone K.
      J. Biol. Chem.280:23936-23944(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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