Cacna2d2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCacna2d2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Cacna2d2(Gene name) > Rat

Cacna2d2 (Gene name),

Voltage-dependent calcium channel subunit alpha-2/delta-2 (Protein name ), CA2D2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacna2d2;

Protein name:

Voltage-dependent calcium channel subunit alpha-2/delta-2;

Alternative:

Voltage-gated calcium channel subunit alpha-2/delta-2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Dimer formed of alpha-2-2 and delta-2 chains; disulfide-linked. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1 (CACNA1), alpha-2 (CACNA2D), beta (CACNB) and delta (CACNA2D) subunits in a 1:1:1:1 ratio.

Function:

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G). Overexpression induces apoptosis.

Subcellular Location:

Membrane Single-pass type I membrane protein Colocalizes with CACNA1A in lipid raft fractions.

Protein Attributes:

Sequence length:

1157

Sequence:

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1050:

1100:

1150:

1157:

FTPSRRL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000021216

String:

Q8CFG6

Pfam:

PF02743

KEGG:

rno:300992

UniGene:

Rn.91563

Uniprot:

Q8CFG6

FOR

ELISA Kit for Rat Voltage-dependent calcium channel subunit alpha-2/delta-2

CLIA Kit for Rat Voltage-dependent calcium channel subunit alpha-2/delta-2

Polyclonal Antibody for Rat Voltage-dependent calcium channel subunit alpha-2/delta-2

Monoclonal Antibody for Rat Voltage-dependent calcium channel subunit alpha-2/delta-2

Protein for Rat Voltage-dependent calcium channel subunit alpha-2/delta-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of calcium channel alpha(2)delta-subunits from rat atria and the differential regulation of their expression by IGF-1."
Chu P.-J. , Best P.M.
J. Mol. Cell. Cardiol.35:207-215(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: Sprague-Dawley.
tissue: Heart atrium.
2.

"Molecular and electrophysiological differences in the L-type Ca2+ channel of the atrium and ventricle of rat hearts."
Hatano S. , Yamashita T. , Sekiguchi A. , Iwasaki Y. , Nakazawa K. , Sagara K. , Iinuma H. , Aizawa T. , Fu L.-T.
Jpn. Circ. J.70:610-614(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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