Cacna2d3 ELISA Kit for Mouse(Mus musculus) | EIAab.comCacna2d3 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Cacna2d3(Gene name) > Mouse

Cacna2d3 (Gene name),

Voltage-dependent calcium channel subunit alpha-2/delta-3 (Protein name ), CA2D3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacna2d3;

Protein name:

Voltage-dependent calcium channel subunit alpha-2/delta-3;

Alternative:

Voltage-gated calcium channel subunit alpha-2/delta-3;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Dimer formed of alpha-2-2 and delta-2 chains; disulfide-linked. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1 (CACNA1), alpha-2 (CACNA2D), beta (CACNB) and delta (CACNA2D) subunits in a 1:1:1:1 ratio.

Function:

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G).

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

1091

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1091:

RPESCHGFHP | EENARECGGA | SSLQAQAALL | LLPLVSSLFS | R

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9Z1L5

UniGene:

Mm.386754

Pfam:

PF02743

KEGG:

mmu:12294

SMR:

Q9Z1L5

STRING:

10090.ENSMUSP00000022567

Uniprot:

Q9Z1L5

FOR

ELISA Kit for Mouse Voltage-dependent calcium channel subunit alpha-2/delta-3

CLIA Kit for Mouse Voltage-dependent calcium channel subunit alpha-2/delta-3

Polyclonal Antibody for Mouse Voltage-dependent calcium channel subunit alpha-2/delta-3

Monoclonal Antibody for Mouse Voltage-dependent calcium channel subunit alpha-2/delta-3

Protein for Mouse Voltage-dependent calcium channel subunit alpha-2/delta-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular diversity of the calcium channel alpha2delta subunit."
Klugbauer N. , Lacinova L. , Marais E. , Hobom M. , Hofmann F.
J. Neurosci.19:684-691(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
tissue: Brain.
2.

"Absence of modulation of the expressed calcium channel alpha1G subunit by alpha2delta subunits."
Lacinova L. , Klugbauer N. , Hofmann F.
J. Physiol. (Lond.)516:639-645(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
3.

"Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes."
Gong H.C. , Hang J. , Kohler W. , Li L. , Su T.-Z.
J. Membr. Biol.184:35-43(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"Calcium channel alpha(2)delta subunits-structure and Gabapentin binding."
Marais E. , Klugbauer N. , Hofmann F.
Mol. Pharmacol.59:1243-1248(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;GLYCOSYLATION;PROTEOLYTIC PROCESSING;LACK OF GABAPENTIN-BINDING

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