CABP4 ELISA Kit for Human(Homo sapiens) | EIAab.comCABP4 ELISA Kit for Human(Homo sapiens) | EIAab.com

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CABP4 (Gene name),

Calcium-binding protein 4 (Protein name ), CABP4_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

CABP4;

Protein name:

Calcium-binding protein 4(CaBP4);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CACNA1F and CACNA1D (via IQ domain) in a calcium independent manner (By similarity). Interacts (via N-terminus) with UNC119.

Function:

Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.

Subcellular Location:

Cytoplasm Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.

Protein Attributes:

Sequence length:

275

Sequence:

50:

MTTEQARGQQ | GPNLAIGRQK | PPAGVVTPKS | DAEEPPLTRK | RSKKERGLRG |

100:

SRKRTGSSGE | QTGPEAPGSS | NNPPSTGEGP | AGAPPASPGP | ASSRQSHRHR |

150:

PDSLHDAAQR | TYGPLLNRVF | GKDRELGPEE | LDELQAAFEE | FDTDRDGYIS |

200:

HRELGDCMRT | LGYMPTEMEL | LEVSQHIKMR | MGGRVDFEEF | VELIGPKLRE |

250:

ETAHMLGVRE | LRIAFREFDR | DRDGRITVAE | LREAVPALLG | EPLAGPELDE |

275:

MLREVDLNGD | GTVDFDEFVM | MLSRH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

MIM:

KEGG:

SMR:

String:

Pfam:

STRING:

9606.ENSP00000324960

Uniprot:

FOR

ELISA Kit for Human CaBP4

ELISA Kit for Human CaBP4

ELISA Kit for Human CaBP4

CLIA Kit for Human CaBP4

CLIA Kit for Human CaBP4

CLIA Kit for Human CaBP4

Polyclonal Antibody for Human CaBP4

Polyclonal Antibody for Human CaBP4

Polyclonal Antibody for Human CaBP4

Monoclonal Antibody for Human CaBP4

Monoclonal Antibody for Human CaBP4

Monoclonal Antibody for Human CaBP4

Protein for Human CaBP4

Protein for Human CaBP4

Protein for Human CaBP4

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function."
Haeseleer F. , Imanishi Y. , Maeda T. , Possin D.E. , Maeda A. , Lee A. , Rieke F. , Palczewski K.
Nat. Neurosci.7:1079-1087(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Retina.
2.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Lung.
4.

"Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin."
Haeseleer F. , Sokal I. , Verlinde C.L.M.J. , Erdjument-Bromage H. , Tempst P. , Pronin A.N. , Benovic J.L. , Fariss R.N. , Palczewski K.
J. Biol. Chem.275:1247-1260(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
5.

"Membrane targeting of the EF-hand containing calcium-sensing proteins CaBP7 and CaBP8."
McCue H.V. , Burgoyne R.D. , Haynes L.P.
Biochem. Biophys. Res. Commun.380:825-831(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
6.

"Mutations in CABP4, the gene encoding the Ca2+-binding protein 4, cause autosomal recessive night blindness."
Zeitz C. , Kloeckener-Gruissem B. , Forster U. , Kohl S. , Magyar I. , Wissinger B. , Matyas G. , Borruat F.-X. , Schorderet D.F. , Zrenner E. , Munier F.L. , Berger W.
Am. J. Hum. Genet.79:657-667(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CSNB2B CYS-124

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