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Index > Protein center > CALN1(Gene name) > Human
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  • CALN1 (Gene name),
  • Calcium-binding protein 8 (Protein name ),  CABP8_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CALN1(CABP8);
    Protein name:
    Calcium-binding protein 8(CaBP8);
    Alternative:
    Calneuron-1;Calneuron I;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PI4KB. This binding competes with FREQ/NCS1 binding in a calcium-dependent manner.
    Function:
    Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.
    Subcellular Location:
    Golgi apparatus trans-Golgi network membrane Single-pass type IV membrane protein Cytoplasm perinuclear region Cell membrane Single-pass type IV membrane protein
    Protein Attributes:
    Sequence length:
    219
    Sequence:
    50:
    MPFHHVTAGL | LYKGNYLNRS | LSAGSDSEQL | ANISVEELDE | IREAFRVLDR | 
    100:
    DGNGFISKQE | LGMAMRSLGY | MPSEVELAII | MQRLDMDGDG | QVDFDEFMTI | 
    150:
    LGPKLVSSEG | RDGFLGNTID | SIFWQFDMQR | ITLEELKHIL | YHAFRDHLTM | 
    200:
    KDIENIIINE | EESLNETSGN | CQTEFEGVHS | QKQNRQTCVR | KSLICAFAMA | 
    219:
    FIISVMLIAA | NQILRSGME
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    MIM:
    String:
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human CaBP8
    ELISA Kit for Human CaBP8
    ELISA Kit for Human CaBP8
    CLIA Kit for Human CaBP8
    CLIA Kit for Human CaBP8
    CLIA Kit for Human CaBP8
    Polyclonal Antibody for Human CaBP8
    Polyclonal Antibody for Human CaBP8
    Polyclonal Antibody for Human CaBP8
    Monoclonal Antibody for Human CaBP8
    Monoclonal Antibody for Human CaBP8
    Monoclonal Antibody for Human CaBP8
    Protein for Human CaBP8
    Protein for Human CaBP8
    Protein for Human CaBP8

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Identification of a human brain-specific gene, calneuron 1, a new member of the calmodulin superfamily."
      Wu Y.-Q. , Lin X. , Liu C.-M. , Jamrich M. , Shaffer L.G.
      Mol. Genet. Metab.72:343-350(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PRELIMINARY FUNCTION
      tissue: Brain.
    2. 2.
      "Calcium-binding protein with similarity to calmodulin."
      Haeseleer F. , Palczewski K.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Retina.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    4. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "Membrane targeting of the EF-hand containing calcium-sensing proteins CaBP7 and CaBP8."
      McCue H.V. , Burgoyne R.D. , Haynes L.P.
      Biochem. Biophys. Res. Commun.380:825-831(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
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