CACNA1B ELISA Kit for Human(Homo sapiens) | EIAab.comCACNA1B ELISA Kit for Human(Homo sapiens)

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CACNA1B (Gene name),

Voltage-dependent N-type calcium channel subunit alpha-1B (Protein name ), CAC1B_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CACNA1B(CACH5;CACNL1A5);

Protein name:

Voltage-dependent N-type calcium channel subunit alpha-1B;

Alternative:

Calcium channel, L type, alpha-1 polypeptide isoform 5;Brain calcium channel III(BIII);Voltage-gated calcium channel subunit alpha Cav2.2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Multisubunit complex consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interacts with RIMS1 and RIMBP2.

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2339

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2339:

TSQSHPLRRV | PNGYHCTLGL | SSGGRARHSY | HHPDQDHWC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q00975

KEGG:

hsa:774

Pfam:

PF08763

SMR:

Q00975

MIM:

601012

UniGene:

Hs.495522

STRING:

9606.ENSP00000277549

Uniprot:

Q00975

FOR

ELISA Kit for Human Voltage-dependent N-type calcium channel subunit alpha-1B

CLIA Kit for Human Voltage-dependent N-type calcium channel subunit alpha-1B

Polyclonal Antibody for Human Voltage-dependent N-type calcium channel subunit alpha-1B

Monoclonal Antibody for Human Voltage-dependent N-type calcium channel subunit alpha-1B

Protein for Human Voltage-dependent N-type calcium channel subunit alpha-1B

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

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