CACNA1E ELISA Kit for Rabbit(Oryctolagus cuniculus) | EIAab.comCACNA1E ELISA Kit for Rabbit(Oryctolagus cuniculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CACNA1E(Gene name) > Rabbit

CACNA1E (Gene name),

Voltage-dependent R-type calcium channel subunit alpha-1E (Protein name ), CAC1E_RABIT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CACNA1E(CACH6;CACNL1A6);

Protein name:

Voltage-dependent R-type calcium channel subunit alpha-1E;

Alternative:

Calcium channel, L type, alpha-1 polypeptide, isoform 6;Brain calcium channel II(BII);Voltage-gated calcium channel subunit alpha Cav2.3;

Organism:

Rabbit (Oryctolagus cuniculus).

General Annotation

Sub Unit:

Interacts with EFHC1. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2259

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

2000:

2050:

2100:

2150:

2200:

2250:

2259:

LSDTEEDKC

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF08763

STRING:

9986.ENSOCUP00000018322

UniGene:

Ocu.3332

Uniprot:

Q02343

FOR

ELISA Kit for Rabbit Voltage-dependent R-type calcium channel subunit alpha-1E

CLIA Kit for Rabbit Voltage-dependent R-type calcium channel subunit alpha-1E

Polyclonal Antibody for Rabbit Voltage-dependent R-type calcium channel subunit alpha-1E

Monoclonal Antibody for Rabbit Voltage-dependent R-type calcium channel subunit alpha-1E

Protein for Rabbit Voltage-dependent R-type calcium channel subunit alpha-1E

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and characterization of a novel calcium channel from rabbit brain."
Niidome T. , Kim M.S. , Friedrich T. , Mori Y.
FEBS Lett.308:7-13(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS BII-1 AND BII-2)
tissue: Brain.

Product Feedback Wall

* Email:
*Comments: