CACNA1G ELISA Kit for Human(Homo sapiens) | EIAab.comCACNA1G ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CACNA1G(Gene name) > Human

CACNA1G (Gene name),

Voltage-dependent T-type calcium channel subunit alpha-1G (Protein name ), CAC1G_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CACNA1G(KIAA1123);

Protein name:

Voltage-dependent T-type calcium channel subunit alpha-1G;

Alternative:

NBR13;Cav3.1c;Voltage-gated calcium channel subunit alpha Cav3.1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2377

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

2000:

2050:

2100:

2150:

2200:

2250:

2300:

2350:

2377:

SMAASPSPKK | DVLSLSGLSS | DPADLDP

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

MIM:

604065

String:

O43497

KEGG:

hsa:8913

Pfam:

PF00520

SMR:

O43497

UniGene:

Hs.591169

Uniprot:

O43497

FOR

ELISA Kit for Human Voltage-dependent T-type calcium channel subunit alpha-1G

CLIA Kit for Human Voltage-dependent T-type calcium channel subunit alpha-1G

Polyclonal Antibody for Human Voltage-dependent T-type calcium channel subunit alpha-1G

Monoclonal Antibody for Human Voltage-dependent T-type calcium channel subunit alpha-1G

Protein for Human Voltage-dependent T-type calcium channel subunit alpha-1G

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors."
Toyota M. , Ho C. , Ohe-Toyota M. , Baylin S.B. , Issa J.-P.J.
Cancer Res.59:4535-4541(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);GENE STRUCTURE
tissue: Prostatic carcinoma.
2.

"Structure and alternative splicing of the gene encoding alpha1G, a human brain T calcium channel alpha1 subunit."
Mittman S. , Guo J. , Agnew W.S.
Neurosci. Lett.274:143-146(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING (ISOFORMS 4 AND 5)
tissue: Brain.
3.

"Molecular cloning and functional expression of ca(v)3.1c, a T-type calcium channel from human brain."
Cribbs L.L. , Gomora J.C. , Daud A.N. , Lee J.-H. , Perez-Reyes E.
FEBS Lett.466:54-58(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Brain.
4.

"Molecular and functional properties of the human alpha1G subunit that forms T-type calcium channels."
Monteil A. , Chemin J. , Bourinet E. , Mennessier G. , Lory P. , Nargeot J.
J. Biol. Chem.275:6090-6100(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING (ISOFORMS 1-2 AND 6-13)
tissue: Brain.
5.

"Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations."
Emerick M.C. , Stein R. , Kunze R. , McNulty M.M. , Regan M.R. , Hanck D.A. , Agnew W.S.
Proteins64:320-342(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 4; 6; 7; 8; 9; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30; 31; 33; 34 AND 35);DEVELOPMENTAL STAGE
tissue: Brain.
tissue: Fetal brain.
6.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 9)
8.

"Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain."
Hirosawa M. , Nagase T. , Ishikawa K. , Kikuno R. , Nomura N. , Ohara O.
DNA Res.6:329-336(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 550-2377 (ISOFORM 13)
tissue: Brain.
9.

"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
10.

"Molecular characterization of a neuronal low-voltage-activated T-type calcium channel."
Perez-Reyes E. , Cribbs L.L. , Daud A. , Lacerda A.E. , Barclay J. , Williamson M.P. , Fox M. , Rees M. , Lee J.-H.
Nature391:896-900(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1126-1444; 1778-1927 AND 2021-2312
tissue: Brain.

Product Feedback Wall

* Email:
*Comments: