Gene name:
Cacnb2 (Cacnlb2) ;
Protein name:
Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) ;
Alternative:
Calcium channel voltage-dependent subunit beta 2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with RRAD. Interaction with RRAD regulates the trafficking of CACNA1C to the cell membrane. Interacts with CAMK2D.
Function:
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Subcellular Location:
Cell membrane
sarcolemma
Peripheral membrane protein
Cytoplasmic side
Protein Attributes:
50:
MVQSDTSKSP | PVAAVAQESQ | MELLESAAPA | GALGAQSYGK | GARRKNRFKG |
100:
SDGSTSSDTT | SNSFVRQGSA | DSYTSRPSDS | DVSLEEDREA | VRREAERQAQ |
150:
AQLEKAKTKP | VAFAVRTNVR | YSAAQEDDVP | VPGMAISFEA | KDFLHVKEKF |
200:
NNDWWIGRLV | KEGCEIGFIP | SPVKLENMRL | QHEQRAKQGK | FYSSKSGGNS |
250:
SSSLGDIVPS | SRKSTPPSSA | IDIDATGLDA | EENDIPANHR | SPKPSANSVT |
300:
SPHSKEKRMP | FFKKTEHTPP | YDVVPSMRPV | VLVGPSLKGY | EVTDMMQKAL |
350:
FDFLKHRFEG | RISITRVTAD | ISLAKRSVLN | NPSKHAIIER | SNTRSSLAEV |
400:
QSEIERIFEL | ARTLQLVVLD | ADTINHPAQL | SKTSLAPIIV | YVKISSPKVL |
450:
QRLIKSRGKS | QAKHLNVQMV | AADKLAQCPP | QESFDVILDE | NQLEDACEHL |
500:
ADYLEAYWKA | THPPSGNLPN | PLLSRTLASS | TLPLSPTLAS | NSQGSQGDQR |
550:
PDRSAPRSAS | QAEEEPCLEP | VKKSQHRSSS | ATHQNHRSGT | GRGLSRQETF |
600:
DSETQESRDS | AYVEPKEDYS | HEHVDRYVPH | REHNHREETH | SSNGHRHRES |
650:
RHRSRDMGRD | QDHNECIKQR | SRHKSKDRYC | DKEGEVISKR | RNEAGEWNRD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Bovine
Mouse
Rabbit
Human
Polyclonal Antibody for Mouse CAB2
Polyclonal Antibody for Mouse CAB2
Polyclonal Antibody for Mouse CAB2
Polyclonal Antibody for Mouse CAB2
Polyclonal Antibody for Mouse CAB2
Monoclonal Antibody for Mouse CAB2
Monoclonal Antibody for Mouse CAB2
Monoclonal Antibody for Mouse CAB2
Monoclonal Antibody for Mouse CAB2
Monoclonal Antibody for Mouse CAB2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORM 3);FUNCTION
tissue :
Heart .
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 4)
strain :
C57BL/6J .
tissue :
Diencephalon .
tissue :
Olfactory bulb .
tissue :
Retina .
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .