Cacnb2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCacnb2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Cacnb2(Gene name) > Rat

Cacnb2 (Gene name),

Voltage-dependent L-type calcium channel subunit beta-2 (Protein name ), CACB2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacnb2(Cacnlb2);

Protein name:

Voltage-dependent L-type calcium channel subunit beta-2(CAB2);

Alternative:

Calcium channel voltage-dependent subunit beta 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with RRAD. Interaction with RRAD regulates the trafficking of CACNA1C to the cell membrane (By similarity). Interacts with CAMK2D.

Function:

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

Subcellular Location:

Cell membrane sarcolemma Peripheral membrane protein Cytoplasmic side

Protein Attributes:

Sequence length:

655

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

655:

VYIRQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8VGC3

Pfam:

PF00625

KEGG:

rno:116600

SMR:

Q8VGC3

STRING:

10116.ENSRNOP00000037354

UniGene:

Rn.10739

Uniprot:

Q8VGC3

FOR

ELISA Kit for Rat CAB2

CLIA Kit for Rat CAB2

Polyclonal Antibody for Rat CAB2

Monoclonal Antibody for Rat CAB2

Protein for Rat CAB2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel."
Perez-Reyes E. , Castellano A. , Kim H.S. , Bertrand P. , Baggstrom E. , Lacerda A.E. , Wei X.Y. , Birnbaumer L.
J. Biol. Chem.267:1792-1797(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY;ALTERNATIVE SPLICING
tissue: Brain.
2.

"Cloning of a functional splice variant of L-type calcium channel beta2 subunit from rat heart."
Yamada Y. , Nagashima M. , Tsutsuura M. , Kobayashi T. , Seki S. , Makita N. , Horio Y. , Tohse N.
J. Biol. Chem.276:47163-47170(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;ALTERNATIVE SPLICING
strain: Wistar.
tissue: Heart.
3.

"Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells."
Colecraft H.M. , Alseikhan B. , Takahashi S.X. , Chaudhuri D. , Mittman S. , Yegnasubramanian V. , Alvania R.S. , Johns D.C. , Marban E. , Yue D.T.
J. Physiol. (Lond.)541:435-452(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3; 4 AND 5);FUNCTION;SUBCELLULAR LOCATION
strain: Sprague-Dawley.
tissue: Heart.
4.

"Structure of a complex between a voltage-gated calcium channel beta-subunit and an alpha-subunit domain."
Van Petegem F. , Clark K.A. , Chatelain F.C. , Minor D.L. Jr.
Nature429:671-675(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 68-476 IN COMPLEX WITH CACNA1S
5.

"CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations."
Koval O.M. , Guan X. , Wu Y. , Joiner M.L. , Gao Z. , Chen B. , Grumbach I.M. , Luczak E.D. , Colbran R.J. , Song L.S. , Hund T.J. , Mohler P.J. , Anderson M.E.
Proc. Natl. Acad. Sci. U.S.A.107:4996-5000(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CAMK2D;PHOSPHORYLATION AT THR-549 BY CAMK2D

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