NOS1AP ELISA Kit for Human(Homo sapiens) | EIAab.comNOS1AP ELISA Kit for Human(Homo sapiens)

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Index > Protein center > NOS1AP(Gene name) > Human

NOS1AP (Gene name),

Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (Protein name ), CAPON_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NOS1AP(CAPON;KIAA0464);

Protein name:

Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein;

Alternative:

Nitric oxide synthase 1 adaptor protein;C-terminal PDZ ligand of neuronal nitric oxide synthase protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with the PDZ domain of NOS1 or the second PDZ domain of DLG4 through its C-terminus. Interacts with RASD1 and SYN1, SYN2 and SYN3 via its PID domain. Forms a ternary complex with NOS1 and RASD1. Forms a ternary complex with NOS1 and SYN1.

Function:

Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

506

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

506:

DDEIAV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O75052

UniGene:

Hs.731942

UniGene:

Hs.655000

MIM:

605551

Pfam:

PF00640

SMR:

O75052

KEGG:

hsa:9722

STRING:

9606.ENSP00000355133

Uniprot:

O75052

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ELISA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

E8789r

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ELISA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

E8789h

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96T

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ELISA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

E8789m

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Packing:

96T

CLIA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

U8789r

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MSDS:

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Packing:

96T

CLIA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

U8789m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

U8789h

Price:

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MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

P8789Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

P8789Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Cat.:

P8789Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

Protein for Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Characterization of cDNA clones in size-fractionated cDNA libraries from human brain."
Seki N. , Ohira M. , Nagase T. , Ishikawa K. , Miyajima N. , Nakajima D. , Nomura N. , Ohara O.
DNA Res.4:345-349(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
2.

"Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder."
Xu B. , Wratten N. , Charych E.I. , Buyske S. , Firestein B.L. , Brzustowicz L.M.
PLoS Med.2:E263-E263(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);ALTERNATIVE SPLICING
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
tissue: Brain.
5.

"CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95."
Jaffrey S.R. , Snowman A.M. , Eliasson M.J.L. , Cohen N.A. , Snyder S.H.
Neuron20:115-124(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 354-506 (ISOFORM 1);INTERACTION WITH NOS1
6.

"A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization."
Arking D.E. , Pfeufer A. , Post W. , Kao W.H.L. , Newton-Cheh C. , Ikeda M. , West K. , Kashuk C. , Akyol M. , Perz S. , Jalilzadeh S. , Illig T. , Gieger C. , Guo C.-Y. , Larson M.G. , Wichmann H.E. , Marban E. , O'Donnell C.J. , more...
Nat. Genet.38:644-651(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN THE REGULATION OF QT INTERVALS
7.

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
9.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-266;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.

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