Gene name:
Nos1ap (Capon) ;
Protein name:
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein ;
Alternative:
Nitric oxide synthase 1 adaptor protein ;C-terminal PDZ ligand of neuronal nitric oxide synthase protein ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with the PDZ domain of NOS1 or the second PDZ domain of DLG4 through its C-terminus. Interacts with RASD1 and SYN1, SYN2 and SYN3 via its PID domain. Forms a ternary complex with NOS1 and RASD1. Forms a ternary complex with NOS1 and SYN1.
Function:
Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4.
Subcellular Location:
N/A
Protein Attributes:
50:
MPSKTKYNLV | DDGHDLRIPL | HNEDAFQHGI | SFEAKYVGSL | DVPRPNSRVE |
100:
IVAAMRRIRY | EFKAKNIKKK | KVSIMVSVDG | VKVILKKKKK | KKEWTWDESK |
150:
MLVMQDPIYR | IFYVSHDSQD | LKIFSYIARD | GASNIFRCNV | FKSKKKSQAM |
200:
RIVRTVGQAF | EVCHKLSLQH | TQQNADGQED | GESERNSDGS | GDPGRQLTGA |
250:
ERVSTATAEE | TDIDAVEVPL | PGNDILEFSR | GVTDLDAIGK | DGGSHIDTTV |
300:
SPHPQEPMLA | ASPRMLLPSS | SSSKPPGLGT | GTPLSTHHQM | QLLQQLLQQQ |
350:
QQQTQVAVAQ | VHLLKDQLAA | EAAARLEAQA | RVHQLLLQNK | DMLQHISLLV |
400:
KQVQELELKL | SGQSTMGSQD | SLLEITFRSG | ALPVLCESTT | PKPEDLHSPL |
450:
LGAGLADFAH | PVGSPLGRRD | CLVKLECFRF | LPAEDNQPMA | QGEPLLGGLE |
500:
LIKFRESGIA | SEYESNTDES | EERDSWSQEE | LPRLLNVLQR | QELGDSLDDE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH NOS1;MUTAGENESIS OF ILE-501; ALA-502 AND VAL-503
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DLG4
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RASD1 AND NOS1
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NOS1; SYN1; SYN2 AND SYN3