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Index > Protein center > Nos1ap(Gene name) > Rat
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  • Nos1ap (Gene name),
  • Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (Protein name ),  CAPON_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Nos1ap(Capon);
    Protein name:
    Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein;
    Alternative:
    Nitric oxide synthase 1 adaptor protein;C-terminal PDZ ligand of neuronal nitric oxide synthase protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with the PDZ domain of NOS1 or the second PDZ domain of DLG4 through its C-terminus. Interacts with RASD1 and SYN1, SYN2 and SYN3 via its PID domain. Forms a ternary complex with NOS1 and RASD1. Forms a ternary complex with NOS1 and SYN1.
    Function:
    Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    503
    Sequence:
    50:
    MPSKTKYNLV | DDGHDLRIPL | HNEDAFQHGI | SFEAKYVGSL | DVPRPNSRVE | 
    100:
    IVAAMRRIRY | EFKAKNIKKK | KVSIMVSVDG | VKVILKKKKK | KKEWTWDESK | 
    150:
    MLVMQDPIYR | IFYVSHDSQD | LKIFSYIARD | GASNIFRCNV | FKSKKKSQAM | 
    200:
    RIVRTVGQAF | EVCHKLSLQH | TQQNADGQED | GESERNSDGS | GDPGRQLTGA | 
    250:
    ERVSTATAEE | TDIDAVEVPL | PGNDILEFSR | GVTDLDAIGK | DGGSHIDTTV | 
    300:
    SPHPQEPMLA | ASPRMLLPSS | SSSKPPGLGT | GTPLSTHHQM | QLLQQLLQQQ | 
    350:
    QQQTQVAVAQ | VHLLKDQLAA | EAAARLEAQA | RVHQLLLQNK | DMLQHISLLV | 
    400:
    KQVQELELKL | SGQSTMGSQD | SLLEITFRSG | ALPVLCESTT | PKPEDLHSPL | 
    450:
    LGAGLADFAH | PVGSPLGRRD | CLVKLECFRF | LPAEDNQPMA | QGEPLLGGLE | 
    500:
    LIKFRESGIA | SEYESNTDES | EERDSWSQEE | LPRLLNVLQR | QELGDSLDDE | 
    503:
    IAV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    E8789r
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    E8789h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    E8789m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    U8789r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    U8789m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    U8789h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    P8789Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    P8789Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Cat.:
    P8789Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Monoclonal Antibody for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
    Protein for Rat Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

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    Precision
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    Linearity
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    References
    1. 1.
      "CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95."
      Jaffrey S.R. , Snowman A.M. , Eliasson M.J.L. , Cohen N.A. , Snyder S.H.
      Neuron20:115-124(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH NOS1;MUTAGENESIS OF ILE-501; ALA-502 AND VAL-503
    2. 2.
      "Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95."
      Tochio H. , Hung F. , Li M. , Bredt D.S. , Zhang M.
      J. Mol. Biol.295:225-237(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLG4
    3. 3.
      "Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON."
      Fang M. , Jaffrey S.R. , Sawa A. , Ye K. , Luo X. , Snyder S.H.
      Neuron28:183-193(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RASD1 AND NOS1
    4. 4.
      "Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON."
      Jaffrey S.R. , Benfenati F. , Snowman A.M. , Czernik A.J. , Snyder S.H.
      Proc. Natl. Acad. Sci. U.S.A.99:3199-3204(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NOS1; SYN1; SYN2 AND SYN3
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