Gene name:
CAPRIN1 (GPIAP1;GPIP137;M11S1;RNG105) ;
Protein name:
Caprin-1 ;
Alternative:
Cytoplasmic activation- and proliferation-associated protein 1 ;Cell cycle-associated protein 1 ;GPI-anchored protein p137 (GPI-p137;p137GPI) ;GPI-anchored membrane protein 1 ;RNA granule protein 105 ;Membrane component chromosome 11 surface marker 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Function:
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.
Subcellular Location:
Cytoplasm
cytosol
Cell projection
dendrite
Associated with RNA granules.
Protein Attributes:
50:
MPSATSHSGS | GSKSSGPPPP | SGSSGSEAAA | GAGAAAPASQ | HPATGTGAVQ |
100:
TEAMKQILGV | IDKKLRNLEK | KKGKLDDYQE | RMNKGERLNQ | DQLDAVSKYQ |
150:
EVTNNLEFAK | ELQRSFMALS | QDIQKTIKKT | ARREQLMREE | AEQKRLKTVL |
200:
ELQYVLDKLG | DDEVRTDLKQ | GLNGVPILSE | EELSLLDEFY | KLVDPERDMS |
250:
LRLNEQYEHA | SIHLWDLLEG | KEKPVCGTTY | KVLKEIVERV | FQSNYFDSTH |
300:
NHQNGLCEEE | EAASAPAVED | QVPEAEPEPA | EEYTEQSEVE | STEYVNRQFM |
350:
AETQFTSGEK | EQVDEWTVET | VEVVNSLQQQ | PQAASPSVPE | PHSLTPVAQA |
400:
DPLVRRQRVQ | DLMAQMQGPY | NFIQDSMLDF | ENQTLDPAIV | SAQPMNPTQN |
450:
MDMPQLVCPP | VHSESRLAQP | NQVPVQPEAT | QVPLVSSTSE | GYTASQPLYQ |
500:
PSHATEQRPQ | KEPIDQIQAT | ISLNTDQTTA | SSSLPAASQP | QVFQAGTSKP |
550:
LHSSGINVNA | APFQSMQTVF | NMNAPVPPVN | EPETLKQQNQ | YQASYNQSFS |
600:
SQPHQVEQTE | LQQEQLQTVV | GTYHGSPDQS | HQVTGNHQQP | PQQNTGFPRS |
650:
NQPYYNSRGV | SRGGSRGARG | LMNGYRGPAN | GFRGGYDGYR | PSFSNTPNSG |
700:
YTQSQFSAPR | DYSGYQRDGY | QQNFKRGSGQ | SGPRGAPRGR | GGPPRPNRGM |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Human Caprin-1
ELISA Kit for Human Caprin-1
ELISA Kit for Human Caprin-1
ELISA Kit for Human Caprin-1
CLIA Kit for Human Caprin-1
CLIA Kit for Human Caprin-1
CLIA Kit for Human Caprin-1
CLIA Kit for Human Caprin-1
Polyclonal Antibody for Human Caprin-1
Polyclonal Antibody for Human Caprin-1
Polyclonal Antibody for Human Caprin-1
Polyclonal Antibody for Human Caprin-1
Monoclonal Antibody for Human Caprin-1
Monoclonal Antibody for Human Caprin-1
Monoclonal Antibody for Human Caprin-1
Monoclonal Antibody for Human Caprin-1
Protein for Human Caprin-1
Protein for Human Caprin-1
Protein for Human Caprin-1
Protein for Human Caprin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ASP-263
tissue :
Colon .
2.
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Eye .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 29-72
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 56-63; 88-110; 115-125; 148-158; 298-310 AND 634-660;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Colon carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;MULTIMERIZATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH G3BP1;MRNA-BINDING;MUTAGENESIS OF ARG-612; ARG-633 AND ARG-690
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-10;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT PRO-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION