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Index > Protein center > CAPZB(Gene name) > Bovine
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  • CAPZB (Gene name),
  • F-actin-capping protein subunit beta (Protein name ),  CAPZB_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CAPZB;
    Protein name:
    F-actin-capping protein subunit beta;
    Alternative:
    CapZ beta;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit. Interacts with ARHGAP17 and RCSD1/CAPZIP. Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.
    Function:
    F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. The isoform beta-3 may play a role in spermatogenesis. Alternatively, may play a role in later maturation steps such as capacitation and fertilization which involve changes of membrane domains.
    Subcellular Location:
    Cytoplasm cytoskeleton perinuclear theca calyx Sperm head cytoskeletal structure tightly associated to the nucleus.
    Protein Attributes:
    Sequence length:
    301
    Sequence:
    50:
    MHPCRRSLPF | PLNCQLVKVG | TADYGGASDQ | SDQQLDCALD | LMRRLPPQQI | 
    100:
    EKNLSDLIDL | VPSLCEDLLS | SVDQPLKIAR | DKVVGKDYLL | CDYNRDGDSY | 
    150:
    RSPWSNKYDP | PLEDGAMPSA | RLRKLEVEAN | NAFDQYRDLY | FEGGVSSVYL | 
    200:
    WDLDHGFAGV | ILIKKAGDGS | KKIKGCWDSI | HVVEVQEKSS | GRTAHYKLTS | 
    250:
    TVMLWLQTNK | SGSGTMNLGG | SLTRQMEKDE | TVSDCSPHIA | NIGRLVEDME | 
    300:
    NKIRSTLNEI | YFGKTKDIVN | GLRSVQTFAD | KSKQEALKND | LVEALKRKQQ | 
    301:
    C
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    ELISA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    CLIA Kit for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Polyclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Monoclonal Antibody for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta
    Protein for Bovine F-actin-capping protein subunit beta

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    References
    1. 1.
      "CP beta3, a novel isoform of an actin-binding protein, is a component of the cytoskeletal calyx of the mammalian sperm head."
      von Buelow M. , Rackwitz H.-R. , Zimbelmann R. , Franke W.W.
      Exp. Cell Res.233:216-224(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS BETA-2 AND BETA-3);CHARACTERIZATION
      tissue: Sperm.
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BETA-3)
      strain: Crossbred X Angus.
      tissue: Liver.
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