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Index > Protein center > Capzb(Gene name) > Mouse
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  • Capzb (Gene name),
  • F-actin-capping protein subunit beta (Protein name ),  CAPZB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Capzb(Cappb1);
    Protein name:
    F-actin-capping protein subunit beta;
    Alternative:
    CapZ beta;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit. Interacts with ARHGAP17 and RCSD1/CAPZIP. Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53 (By similarity). Isoform 2 also is a component of dynactin complex from brain, which contains the actin-related protein ARP1.
    Function:
    F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    277
    Sequence:
    50:
    MSDQQLDCAL | DLMRRLPPQQ | IEKNLSDLID | LVPSLCEDLL | SSVDQPLKIA | 
    100:
    RDKVVGKDYL | LCDYNRDGDS | YRSPWSNKYD | PPLEDGAMPS | ARLRKLEVEA | 
    150:
    NNAFDQYRDL | YFEGGVSSVY | LWDLDHGFAG | VILIKKAGDG | SKKIKGCWDS | 
    200:
    IHVVEVQEKS | SGRTAHYKLT | STVMLWLQTN | KSGSGTMNLG | GSLTRQMEKD | 
    250:
    ETVSDCSPHI | ANIGRLVEDM | ENKIRSTLNE | IYFGKTKDIV | NGLRSLDAIP | 
    277:
    DNHKFKQLQR | ELSQVLTQRQ | VYIQPDN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    ELISA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    CLIA Kit for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Polyclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Monoclonal Antibody for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta
    Protein for Mouse F-actin-capping protein subunit beta

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    References
    1. 1.
      "Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates."
      Schafer D.A. , Korshunova Y.O. , Schroer T.A. , Cooper J.A.
      J. Cell Biol.127:453-465(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Skeletal muscle.
    2. 2.
      "A missense mutation in the Capza3 gene and disruption of F-actin organization in spermatids of repro32 infertile male mice."
      Geyer C.B. , Inselman A.L. , Sunman J.A. , Bornstein S. , Handel M.A. , Eddy E.M.
      Dev. Biol.330:142-152(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: CD-1.
      tissue: Testis.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Lubec G. , Klug S. , Yang J.W. , Zigmond M.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 79-92 AND 169-181;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Hippocampus.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    6. 6.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-235;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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