Carm1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCarm1 ELISA Kit for Rat(Rattus norvegicus)

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Carm1 (Gene name),

Histone-arginine methyltransferase CARM1 (Protein name ), CARM1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Carm1(Prmt4);

Protein name:

Histone-arginine methyltransferase CARM1;

Alternative:

Protein arginine N-methyltransferase 4;Coactivator-associated arginine methyltransferase 1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer (Probable). Interacts with NR1H4. Interacts with the C-terminus of NCOA2/GRIP1, NCO3/ACTR and NCOA1/SRC1. Part of a complex consisting of CARM1, EP300/P300 and NCOA2/GRIP1. Interacts with FLII, TP53, myogenic factor MEF2, EP300/P300, TRIM24, CREBBP and CTNNB1. Identified in a complex containing CARM1, TRIM24 and NCOA2/GRIP1. Interacts with NCOA3/SRC3. Interacts with RELA (By similarity). Interacts with SNRPC.

Function:

Isoform 3 specifically affects pre-mRNA splicing. This activity is independent from methyltransferase activity.

Subcellular Location:

Nucleus Cytoplasm Mainly nuclear during the G1, S and G2 phases of the cell cycle. Cytoplasmic during mitosis, after breakup of the nuclear membrane.

Protein Attributes:

Sequence length:

651

Sequence:

50:

100:

150:

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300:

350:

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450:

500:

550:

600:

650:

651:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q4AE70

STRING:

10116.ENSRNOP00000049428

UniGene:

Rn.94869

KEGG:

rno:363026

String:

Q4AE70

Pfam:

PF11531

Uniprot:

Q4AE70

FOR

ELISA Kit for Rat Histone-arginine methyltransferase CARM1

CLIA Kit for Rat Histone-arginine methyltransferase CARM1

Polyclonal Antibody for Rat Histone-arginine methyltransferase CARM1

Monoclonal Antibody for Rat Histone-arginine methyltransferase CARM1

Protein for Rat Histone-arginine methyltransferase CARM1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Coactivator-associated arginine methyltransferase 1, CARM1, affects pre-mRNA splicing in an isoform-specific manner."
Ohkura N. , Takahashi M. , Yaguchi H. , Nagamura Y. , Tsukada T.
J. Biol. Chem.280:28927-28935(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);FUNCTION OF ISOFORM 3;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INTERACTION WITH SNRPC
tissue: Fetal brain.
2.

"CARM1 regulates proliferation of PC12 cells by methylating HuD."
Fujiwara T. , Mori Y. , Chu D.L. , Koyama Y. , Miyata S. , Tanaka H. , Yachi K. , Kubo T. , Yoshikawa H. , Tohyama M.
Mol. Cell. Biol.26:2273-2285(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION OF ELAV4;SUBCELLULAR LOCATION
3.

"Functional insights from structures of coactivator-associated arginine methyltransferase 1 domains."
Troffer-Charlier N. , Cura V. , Hassenboehler P. , Moras D. , Cavarelli J.
EMBO J.26:4391-4401(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS) OF 28-507 IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE;SUBUNIT;IDENTIFICATION BY MASS SPECTROMETRY

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