Casp3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCasp3 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Casp3(Gene name) > Rat

Casp3 (Gene name),

Caspase-3 (Protein name ), CASP3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

Casp3(Cpp32);

Protein name:

Caspase-3(CASP-3);

Alternative:

Cysteine protease CPP32(CPP-32);Apopain;LICE;IRP;SREBP cleavage activity 1(SCA-1);Protein Yama;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit.

Function:

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

277

Sequence:

50:

100:

150:

200:

250:

277:

SLDATFHAKK | QIPCIVSMLT | KELYFYH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.10562

Pfam:

PF00656

SMR:

P55213

String:

P55213

KEGG:

rno:25402

Uniprot:

P55213

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ELISA Kit for Rat CASP-3

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E0626b

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ELISA Kit for Rat CASP-3

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E0626h

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ELISA Kit for Rat CASP-3

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E0626m

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ELISA Kit for Rat CASP-3

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E0626r

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ELISA Kit for Rat CASP-3

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E0626p

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ELISA Kit for Rat CASP-3

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ELISA Kit for Rat CASP-3

Cat.:

E0626d

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96T

CLIA Kit for Rat CASP-3

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CLIA Kit for Rat CASP-3

Cat.:

U0626h

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96T

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CLIA Kit for Rat CASP-3

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U0626p

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96T

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CLIA Kit for Rat CASP-3

Cat.:

U0626m

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96T

CLIA Kit for Rat CASP-3

Cat.:

U0626d

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96T

CLIA Kit for Rat CASP-3

Cat.:

U0626r

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96T

CLIA Kit for Rat CASP-3

Cat.:

U0626b

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96T

Polyclonal Antibody for Rat CASP-3

Cat.:

P0626Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat CASP-3

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P0626Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat CASP-3

Cat.:

P0626Rb-r

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Polyclonal Antibody for Rat CASP-3

Monoclonal Antibody for Rat CASP-3

Protein for Rat CASP-3

Cat.:

R0626h

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"Renoprotective effect of Spirulina platensis extract against nicotine-induced oxidative stress-mediated inflammation in rats"

W E. Zahran, M A. Emam.

From:Phytomedicine

[2].

"Protective role of ellagitannins from Eucalyptus citriodora against ethanol-induced gastric ulcer in rats: Impact on oxidative..."

Eman AS, Reem NE

From:Phytomedicine

References

1.

"Molecular characterization of mouse and rat CPP32 beta gene encoding a cysteine protease resembling interleukin-1 beta converting enzyme and CED-3."
Juan T.S.-C. , McNiece I.K. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Fletcher F.A.
Oncogene13:749-755(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons."
Ni B. , Wu X. , Du Y. , Su Y. , Hamilton-Byrd E. , Rockey P.K. , Rosteck P. Jr. , Poirier G.G. , Paul S.M.
J. Neurosci.17:1561-1569(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Heart.
4.

"Cloning of the rat cysteine protease p32-beta."
Yakovlev A.G.
Submitted (1996-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-264
5.

"Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle."
Flaws J.A. , Kugu K. , Trbovich A.M. , Desanti A. , Tilly K.I. , Hirshfield A.N. , Tilly J.L.
Endocrinology136:5042-5053(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 30-241
tissue: Ovary.

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