Gene name:
CAPZA3 (CAPAA3;GSG3) ;
Protein name:
F-actin-capping protein subunit alpha-3 ;
Alternative:
Germ cell-specific protein 3 ;CapZ alpha-3 (CP-alpha-3) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Heterodimer of an alpha and a beta subunit (By similarity). Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.
Function:
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid.
Subcellular Location:
N/A
Protein Attributes:
50:
MTLSVLSRKD | KERVIRRLLL | QAPPGEFVNA | FDDLCLLIRD | EKLMHHQGEC |
100:
AGHQHCQKYS | VPLCIDGNPV | LLSHHNVMGD | YRFFDHQSKL | SFKYDLLQNQ |
150:
LKDIQSHGII | QNEAEYLRVV | LLCALKLYVN | DHYPKGNCNM | LRKTVKSKEY |
200:
LIACIEDHNY | ETGECWNGLW | KSKWIFQVNP | FLTQVTGRIF | VQAHFFRCVN |
250:
LHIEISKDLK | ESLEIVNQAQ | LALSFARLVE | EQENKFQAAV | LEELQELSNE |
299:
ALRKILRRDL | PVTRTLIDWH | RILSDLNLVM | YPKLGYVIYS | RSVLCNWII
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Human F-actin-capping protein subunit alpha-3
ELISA Kit for Human F-actin-capping protein subunit alpha-3
ELISA Kit for Human F-actin-capping protein subunit alpha-3
CLIA Kit for Human F-actin-capping protein subunit alpha-3
CLIA Kit for Human F-actin-capping protein subunit alpha-3
CLIA Kit for Human F-actin-capping protein subunit alpha-3
Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
Protein for Human F-actin-capping protein subunit alpha-3
Protein for Human F-actin-capping protein subunit alpha-3
Protein for Human F-actin-capping protein subunit alpha-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue :
Testis .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE WASH COMPLEX