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Index > Protein center > CAPZA3(Gene name) > Human
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  • CAPZA3 (Gene name),
  • F-actin-capping protein subunit alpha-3 (Protein name ),  CAZA3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CAPZA3(CAPAA3;GSG3);
    Protein name:
    F-actin-capping protein subunit alpha-3;
    Alternative:
    Germ cell-specific protein 3;CapZ alpha-3(CP-alpha-3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of an alpha and a beta subunit (By similarity). Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.
    Function:
    F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    299
    Sequence:
    50:
    MTLSVLSRKD | KERVIRRLLL | QAPPGEFVNA | FDDLCLLIRD | EKLMHHQGEC | 
    100:
    AGHQHCQKYS | VPLCIDGNPV | LLSHHNVMGD | YRFFDHQSKL | SFKYDLLQNQ | 
    150:
    LKDIQSHGII | QNEAEYLRVV | LLCALKLYVN | DHYPKGNCNM | LRKTVKSKEY | 
    200:
    LIACIEDHNY | ETGECWNGLW | KSKWIFQVNP | FLTQVTGRIF | VQAHFFRCVN | 
    250:
    LHIEISKDLK | ESLEIVNQAQ | LALSFARLVE | EQENKFQAAV | LEELQELSNE | 
    299:
    ALRKILRRDL | PVTRTLIDWH | RILSDLNLVM | YPKLGYVIYS | RSVLCNWII
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    MIM:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human F-actin-capping protein subunit alpha-3
    ELISA Kit for Human F-actin-capping protein subunit alpha-3
    ELISA Kit for Human F-actin-capping protein subunit alpha-3
    CLIA Kit for Human F-actin-capping protein subunit alpha-3
    CLIA Kit for Human F-actin-capping protein subunit alpha-3
    CLIA Kit for Human F-actin-capping protein subunit alpha-3
    Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Polyclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Monoclonal Antibody for Human F-actin-capping protein subunit alpha-3
    Protein for Human F-actin-capping protein subunit alpha-3
    Protein for Human F-actin-capping protein subunit alpha-3
    Protein for Human F-actin-capping protein subunit alpha-3

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    References
    1. 1.
      "Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3)."
      Miyagawa Y. , Tanaka H. , Iguchi N. , Kitamura K. , Nakamura Y. , Takahashi T. , Matsumiya K. , Okuyama A. , Nishimune Y.
      Mol. Hum. Reprod.8:531-539(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      tissue: Testis.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    4. 4.
      "The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex."
      Derivery E. , Sousa C. , Gautier J.J. , Lombard B. , Loew D. , Gautreau A.
      Dev. Cell17:712-723(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE WASH COMPLEX
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