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Index > Protein center > Cbs(Gene name) > Mouse
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  • Cbs (Gene name),
  • Cystathionine beta-synthase (Protein name ),  CBS_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Cbs;
    Protein name:
    Cystathionine beta-synthase;
    Alternative:
    Serine sulfhydrase;Beta-thionase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    561
    Sequence:
    50:
    MPSGTSQCED | GSAGGFQHLD | MHSEKRQLEK | GPSGDKDRVW | IRPDTPSRCT | 
    100:
    WQLGRAMADS | PHYHTVLTKS | PKILPDILRK | IGNTPMVRIN | KISKNAGLKC | 
    150:
    ELLAKCEFFN | AGGSVKDRIS | LRMIEDAERA | GNLKPGDTII | EPTSGNTGIG | 
    200:
    LALAAAVKGY | RCIIVMPEKM | SMEKVDVLRA | LGAEIVRTPT | NARFDSPESH | 
    250:
    VGVAWRLKNE | IPNSHILDQY | RNASNPLAHY | DDTAEEILQQ | CDGKLDMLVA | 
    300:
    SAGTGGTITG | IARKLKEKCP | GCKIIGVDPE | GSILAEPEEL | NQTEQTAYEV | 
    350:
    EGIGYDFIPT | VLDRAVVDKW | FKSNDEDSFA | FARMLIAQEG | LLCGGSSGSA | 
    400:
    MAVAVKAARE | LQEGQRCVVI | LPDSVRNYMS | KFLSDKWMLQ | KGFMKEELSV | 
    450:
    KRPWWWRLRV | QELSLSAPLT | VLPTVTCEDT | IAILREKGFD | QAPVVNESGA | 
    500:
    ILGMVTLGNM | LSSLLAGKVR | PSDEVCKVLY | KQFKPIHLTD | TLGTLSHILE | 
    550:
    MDHFALVVHE | QIQSRDQAWS | GVVGGPTDCS | NGMSSKQQMV | FGVVTAIDLL | 
    561:
    NFVAAREQTQ | T
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    E1957h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    E1957r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    E1957m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cystathionine beta-synthase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    U1957m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cystathionine beta-synthase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    U1957h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Cystathionine beta-synthase
    Cat.:
    U1957r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cystathionine beta-synthase
    Polyclonal Antibody for Mouse Cystathionine beta-synthase
    Cat.:
    P1957Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cystathionine beta-synthase
    Cat.:
    P1957Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cystathionine beta-synthase
    Cat.:
    P1957Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cystathionine beta-synthase
    Monoclonal Antibody for Mouse Cystathionine beta-synthase
    Monoclonal Antibody for Mouse Cystathionine beta-synthase
    Monoclonal Antibody for Mouse Cystathionine beta-synthase
    Protein for Mouse Cystathionine beta-synthase
    Protein for Mouse Cystathionine beta-synthase
    Protein for Mouse Cystathionine beta-synthase
    Protein for Mouse Cystathionine beta-synthase

    R&D Technical Data
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    s

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤9.5%

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Recovery was determined by spiking various levels of CBS into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    101

    95-103

    Plasma

    103

    97-107

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of CBS and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    95-107%

    94-109%

    97-104%

    99-103%

    Saliva(n=3)

    93-105%

    96-103%

    97-104%

    95-106%

    heparin plasma(n=5)

    98-108%

     

    94-110%

    99-106%

    96-109%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Kidney.
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