Gene name:
CCNDBP1 (DIP1;GCIP;HHM) ;
Protein name:
Cyclin-D1-binding protein 1 ;
Alternative:
Human homolog of Maid ;Grap2 and cyclin-D-interacting protein ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.
Function:
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MASATAPAAA | VPTLASPLEQ | LRHLAEELRL | LLPRVRVGEA | QETTEEFNRE |
100:
MFWRRLNEAA | VTVSREATTL | TIVFSQLPLP | SPQETQKFCE | QVHAAIKAFI |
150:
AVYYLLPKDQ | GITLRKLVRG | ATLDIVDGMA | QLMEVLSVTP | TQSPENNDLI |
200:
SYNSVWVACQ | QMPQIPRDNK | AAALLMLTKN | VDFVKDAHEE | MEQAVEECDP |
250:
YSGLLNDTEE | NNSDNHNHED | DVLGFPSNQD | LYWSEDDQEL | IIPCLALVRA |
300:
SKACLKKIRM | LVAENGKKDQ | VAQLDDIVDI | SDEISPSVDD | LALSIYPPMC |
350:
HLTVRINSAK | LVSVLKKALE | ITKASHVTPQ | PEDSWIPLLI | NAIDHCMNRI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Bovine
Mouse
Human
ELISA Kit for Human Cyclin-D1-binding protein 1
ELISA Kit for Human Cyclin-D1-binding protein 1
ELISA Kit for Human Cyclin-D1-binding protein 1
ELISA Kit for Human Cyclin-D1-binding protein 1
CLIA Kit for Human Cyclin-D1-binding protein 1
CLIA Kit for Human Cyclin-D1-binding protein 1
CLIA Kit for Human Cyclin-D1-binding protein 1
CLIA Kit for Human Cyclin-D1-binding protein 1
Polyclonal Antibody for Human Cyclin-D1-binding protein 1
Polyclonal Antibody for Human Cyclin-D1-binding protein 1
Polyclonal Antibody for Human Cyclin-D1-binding protein 1
Polyclonal Antibody for Human Cyclin-D1-binding protein 1
Monoclonal Antibody for Human Cyclin-D1-binding protein 1
Monoclonal Antibody for Human Cyclin-D1-binding protein 1
Monoclonal Antibody for Human Cyclin-D1-binding protein 1
Monoclonal Antibody for Human Cyclin-D1-binding protein 1
Protein for Human Cyclin-D1-binding protein 1
Protein for Human Cyclin-D1-binding protein 1
Protein for Human Cyclin-D1-binding protein 1
Protein for Human Cyclin-D1-binding protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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Exp. Cell Res.257:22-32(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH CCND1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;PHOSPHORYLATION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH TCF3;TISSUE SPECIFICITY
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH CCND1 AND GRAP2;TISSUE SPECIFICITY
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
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"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
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Proc. Natl. Acad. Sci. U.S.A.97:9543-9548(2000)
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue :
Hypothalamus .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
7.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4)
tissue :
Hair follicle dermal papilla .
tissue :
Lung .
tissue :
Retinoblastoma .
tissue :
Trachea .
8.
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DNA Res.12:117-126(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Placenta .
9.
Mural R.J.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Pancreas .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SYF2
12.
"Human homologue of maid is a useful marker protein in hepatocarcinogenesis."
Takami T.
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Terai S.
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Yokoyama Y.
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Tanimoto H.
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Gastroenterology128:1369-1380(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;INTERACTION WITH COPS5
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SIRT6;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RPLP0;SUBCELLULAR LOCATION
15.
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P.
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Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]