Cacng2 ELISA Kit for Mouse(Mus musculus) | EIAab.comCacng2 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Cacng2(Gene name) > Mouse

Cacng2 (Gene name),

Voltage-dependent calcium channel gamma-2 subunit (Protein name ), CCG2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacng2(Stg);

Protein name:

Voltage-dependent calcium channel gamma-2 subunit;

Alternative:

Stargazin;Neuronal voltage-gated calcium channel gamma-2 subunit;Transmembrane AMPAR regulatory protein gamma-2(TARP gamma-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Interacts with the PDZ domains of DLG4/PSD-95 and DLG1/SAP97. May interact with GOPC. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with GRIA1.

Function:

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

323

Sequence:

50:

100:

150:

200:

250:

300:

323:

NCIQKDSKDS | LHANTANRRT | TPV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00822

STRING:

10090.ENSMUSP00000019290

UniGene:

Mm.277338

String:

O88602

KEGG:

mmu:12300

Uniprot:

O88602

FOR

ELISA Kit for Mouse Voltage-dependent calcium channel gamma-2 subunit

CLIA Kit for Mouse Voltage-dependent calcium channel gamma-2 subunit

Polyclonal Antibody for Mouse Voltage-dependent calcium channel gamma-2 subunit

Monoclonal Antibody for Mouse Voltage-dependent calcium channel gamma-2 subunit

Protein for Mouse Voltage-dependent calcium channel gamma-2 subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit."
Letts V.A. , Felix R. , Biddlecome G.H. , Arikkath J. , Mahaffey C.L. , Valenzuela A. , Bartlett F.S. II , Mori Y. , Campbell K.P. , Frankel W.N.
Nat. Genet.19:340-347(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: ICR.
tissue: Brain.
2.

"Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95."
Choi J. , Ko J. , Park E. , Lee J.-R. , Yoon J. , Lim S. , Kim E.
J. Biol. Chem.277:12359-12363(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-321;INTERACTION WITH DLG1 AND DLG4;MUTAGENESIS OF THR-321 AND VAL-323
3.

"Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo."
Ives J.H. , Fung S. , Tiwari P. , Payne H.L. , Thompson C.L.
J. Biol. Chem.279:31002-31009(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GOPC
4.

"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-271;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.

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