Cacng4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCacng4 ELISA Kit for Rat(Rattus norvegicus)

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Cacng4 (Gene name),

Voltage-dependent calcium channel gamma-4 subunit (Protein name ), CCG4_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacng4;

Protein name:

Voltage-dependent calcium channel gamma-4 subunit;

Alternative:

Transmembrane AMPAR regulatory protein gamma-4(TARP gamma-4);Neuronal voltage-gated calcium channel gamma-4 subunit;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG5, CACNG7 and CACNG8.

Function:

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

327

Sequence:

50:

100:

150:

200:

250:

300:

327:

LQMHDFFQQD | LKEGFHVSML | NRRTTPV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.162211

Pfam:

PF00822

STRING:

10116.ENSRNOP00000004383

KEGG:

rno:140725

String:

Q8VHW9

Uniprot:

Q8VHW9

FOR

ELISA Kit for Rat Voltage-dependent calcium channel gamma-4 subunit

CLIA Kit for Rat Voltage-dependent calcium channel gamma-4 subunit

Polyclonal Antibody for Rat Voltage-dependent calcium channel gamma-4 subunit

Monoclonal Antibody for Rat Voltage-dependent calcium channel gamma-4 subunit

Protein for Rat Voltage-dependent calcium channel gamma-4 subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Calcium channel gamma subunits provide insights into the evolution of this gene family."
Chu P.-J. , Robertson H.M. , Best P.M.
Gene280:37-48(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Sprague-Dawley.
2.

"TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating."
Milstein A.D. , Zhou W. , Karimzadegan S. , Bredt D.S. , Nicoll R.A.
Neuron55:905-918(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
3.

"Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5."
Soto D. , Coombs I.D. , Renzi M. , Zonouzi M. , Farrant M. , Cull-Candy S.G.
Nat. Neurosci.12:277-285(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
4.

Soto D. , Coombs I.D. , Renzi M. , Zonouzi M. , Farrant M. , Cull-Candy S.G.
Nat. Neurosci.12:808-808(2009)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
5.

"Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors."
Schwenk J. , Harmel N. , Zolles G. , Bildl W. , Kulik A. , Heimrich B. , Chisaka O. , Jonas P. , Schulte U. , Fakler B. , Kloecker N.
Science323:1313-1319(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;IDENTIFICATION BY MASS SPECTROMETRY

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