CCL18 ELISA Kit for Human(Homo sapiens) | EIAab.comCCL18 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CCL18(Gene name) > Human

CCL18 (Gene name),

C-C motif chemokine 18 (Protein name ), CCL18_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CCL18(AMAC1;DCCK1;MIP4;PARC;SCYA18);

Protein name:

C-C motif chemokine 18;

Alternative:

CC chemokine PARC;Alternative macrophage activation-associated CC chemokine 1(AMAC-1);Macrophage inflammatory protein 4(MIP-4);Dendritic cell chemokine 1(DC-CK1);Small-inducible cytokine A18;Pulmonary and activation-regulated chemokine;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

89:

SPQCPKPGVI | LLTKRGRQIC | ADPNKKWVQK | YISDLKLNA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:6362

Pfam:

PF00048

UniGene:

Hs.143961

SMR:

P55774

MIM:

603757

STRING:

9606.ENSP00000004921

String:

P55774

Uniprot:

P55774

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ELISA Kit for Human C-C motif chemokine 18

Cat.:

E0211h

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Manual:

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Packing:

96T

Range:

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CLIA Kit for Human C-C motif chemokine 18

Cat.:

U0211h

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MSDS:

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Packing:

96T

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Polyclonal Antibody for Human C-C motif chemokine 18

Cat.:

P0211Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human C-C motif chemokine 18

Protein for Human C-C motif chemokine 18

Cat.:

R0211h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Macrophage inflammatory protein-3 and -4."
Li H. , Ruben S.

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes."
Hieshima K. , Imai T. , Baba M. , Shoudai K. , Ishizuka K. , Nakagawa T. , Tsuruta J. , Takeya M. , Sakaki Y. , Takatsuki K. , Miura R. , Opdenakker G. , van Damme J. , Yoshie O. , Nomiyama H.
J. Immunol.159:1140-1149(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue: Aorta.
tissue: Lung.
3.

"Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern."
Kodelja V. , Mueller C. , Politz O. , Hakij N. , Orfanos C.E. , Goerdt S.
J. Immunol.160:1411-1418(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells."
Adema G.J. , Hartgers F. , Verstraten R. , de Vries E. , Marland G. , Menon S. , Foster J. , Xu Y. , Nooyen P. , McClanahan T. , Bacon K.B. , Figdor C.G.
Nature387:713-717(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS
tissue: Dendritic cell.
5.

"Chemokine PARC gene (SCYA18) generated by fusion of two MIP-1alpha/LD78alpha-like genes."
Tasaki Y. , Fukuda S. , Iio M. , Miura R. , Imai T. , Sugano S. , Yoshie O. , Hughes A.L. , Nomiyama H.
Genomics55:353-357(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18."
Guan P. , Burghes A.H.M. , Cunningham A. , Lira P. , Brissette W.H. , Neote K. , McColl S.R.
Genomics56:296-302(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];CHARACTERIZATION
7.

"The genomic locus for the AMAC-1 gene contains possible pseudo-exons within the first intron sequence."
Politz O. , Kodelja V. , Guillot P. , Orfanos C.E. , Goerdt S.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
8.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
Goshima N. , Kawamura Y. , Fukumoto A. , Miura A. , Honma R. , Satoh R. , Wakamatsu A. , Yamamoto J. , Kimura K. , Nishikawa T. , Andoh T. , Iida Y. , Ishikawa K. , Ito E. , Kagawa N. , Kaminaga C. , Kanehori K. , Kawakami B. , more...
Nat. Methods5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
12.

"The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases."
Wells T.N.C. , Peitsch M.C.
J. Leukoc. Biol.61:545-550(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISCUSSION OF SEQUENCE
13.

"Selective induction of CCL18/PARC by staphylococcal enterotoxins in mononuclear cells and enhanced levels in septic and rheumatoid arthritis."
Schutyser E. , Struyf S. , Wuyts A. , Put W. , Geboes K. , Grillet B. , Opdenakker G. , Van Damme J.
Eur. J. Immunol.31:3755-3762(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF CCL18(3-69) AND CCL18(4-69);PROTEOLYTIC PROCESSING OF N-TERMINAL;FUNCTION;MASS SPECTROMETRY;TISSUE SPECIFICITY;INDUCTION
14.

"Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma."
Schutyser E. , Struyf S. , Proost P. , Opdenakker G. , Laureys G. , Verhasselt B. , Peperstraete L. , Van de Putte I. , Saccani A. , Allavena P. , Mantovani A. , Van Damme J.
J. Biol. Chem.277:24584-24593(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF CCL18(1-68);PROTEOLYTIC PROCESSING OF C-TERMINAL;FUNCTION
15.

"The disulfide bond between cysteine 10 and cysteine 34 is required for CCL18 activity."
Legendre B. , Tokarski C. , Chang Y. , De Freitas Caires N. , Lortat-Jacob H. , Nadai P.D. , Rolando C. , Duez C. , Tsicopoulos A. , Lassalle P.
Cytokine64:463-470(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS

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