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Index > Protein center > Ccr4(Gene name) > Mouse
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  • Ccr4 (Gene name),
  • C-C chemokine receptor type 4 (Protein name ),  CCR4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccr4(Cmkbr4);
    Protein name:
    C-C chemokine receptor type 4(C-C CKR-4;CC-CKR-4;CCR-4;CCR4);
    Alternative:

    CD:
    CD194;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could mediate hippocampal-neuron survival.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    360
    Sequence:
    50:
    MNATEVTDTT | QDETVYNSYY | FYESMPKPCT | KEGIKAFGEV | FLPPLYSLVF | 
    100:
    LLGLFGNSVV | VLVLFKYKRL | KSMTDVYLLN | LAISDLLFVL | SLPFWGYYAA | 
    150:
    DQWVFGLGLC | KIVSWMYLVG | FYSGIFFIML | MSIDRYLAIV | HAVFSLKART | 
    200:
    LTYGVITSLI | TWSVAVFASL | PGLLFSTCYT | EHNHTYCKTQ | YSVNSTTWKV | 
    250:
    LSSLEINVLG | LLIPLGIMLF | CYSMIIRTLQ | HCKNEKKNRA | VRMIFAVVVL | 
    300:
    FLGFWTPYNV | VLFLETLVEL | EVLQDCTLER | YLDYAIQATE | TLAFIHCCLN | 
    350:
    PVIYFFLGEK | FRKYITQLFR | TCRGPLVLCK | HCDFLQVYSA | DMSSSSYTQS | 
    360:
    TVDHDFRDAL | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C CKR-4
    Cat.:
    E1920m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse C-C CKR-4
    Cat.:
    E1920h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse C-C CKR-4
    Cat.:
    E1920d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C CKR-4
    Cat.:
    U1920h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C CKR-4
    Cat.:
    U1920d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C CKR-4
    Cat.:
    U1920m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse C-C CKR-4
    Cat.:
    P1920Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C CKR-4
    Cat.:
    P1920Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C CKR-4
    Monoclonal Antibody for Mouse C-C CKR-4
    Monoclonal Antibody for Mouse C-C CKR-4
    Monoclonal Antibody for Mouse C-C CKR-4
    Protein for Mouse C-C CKR-4
    Protein for Mouse C-C CKR-4
    Protein for Mouse C-C CKR-4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of murine CC CKR-4 and high affinity binding of chemokines to murine and human CC CKR-4."
      Hoogewerf A.J. , Black D. , Proudfoot A.E.I. , Wells T.N.C. , Power C.A.
      Biochem. Biophys. Res. Commun.218:337-343(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6 X CBA.
      tissue: Thymus.
    2. 2.
      "Molecular cloning and characterization of a cDNA, CHEMR1, encoding a chemokine receptor with a homology to the human C-C chemokine receptor, CCR-4."
      Youn B.-S. , Kim S.-H. , Lyu M.S. , Kozak C.A. , Taub D.D. , Kwon B.S.
      Blood89:4448-4460(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Cytotoxic T-cell.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thymus.
    5. 5.
      "A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock."
      Buser R. , Conquet F. , Proudfoot A.E.I. , Wells T.N.C. , Power C.A.
      J. Exp. Med.191:1755-1764(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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