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Index > Protein center > CCSAP(Gene name) > Human
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  • CCSAP (Gene name),
  • Centriole, cilia and spindle-associated protein (Protein name ),  CCSAP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCSAP(C1orf96;CSAP);
    Protein name:
    Centriole, cilia and spindle-associated protein;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Associates with microtubules; the association occurs on polyglutamylated tubulin.
    Function:
    May play a role in embryonic development. May be required for proper cilia beating.
    Subcellular Location:
    Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriole Cytoplasm Cytoskeleton Spindle Cytoplasm Cytoskeleton Cytoplasm Cytoskeleton Cilium basal body Cytoplasm Cytoskeleton Cilium axoneme Cell projection Axon Cell projection Cilium Localizes to two to four centrioles throughout the cell cycle. Localizes to mitotic spindle microtubules during prometaphase and throughout the remainder of mitosis. Localizes to cytoskeleton on interphase. Localizes at the ciliary transition zone which connects the basal bodies to ciliary microtubules. Colocalizes with polyglutamylated tubulin.
    Protein Attributes:
    Sequence length:
    270
    Sequence:
    50:
    MSPGSGVKSE | YMKRYQEPRW | EEYGPCYREL | LHYRLGRRLL | EQAHAPWLWD | 
    100:
    DWGPAGSSED | SASSESSGAG | GPAPRCAPPS | PPPPVEPATQ | EEAERRARGA | 
    150:
    PEEQDAEAGD | AEAEDAEDAA | LPALPVKDVE | DKPEQQTRTR | ETDKSPTSTE | 
    200:
    PRQQPSALFA | RGNRKAVKSP | QRSSSKIKEN | KHPFALYGWG | EKQTDTGSQK | 
    250:
    THNVCASAPV | HEIHESALRA | KNRRQVEKRK | LVAQRQRAHS | VDVEKNRKMK | 
    270:
    ASSSENPWMT | EYMRCYSARA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Centriole, cilia and spindle-associated protein
    ELISA Kit for Human Centriole, cilia and spindle-associated protein
    CLIA Kit for Human Centriole, cilia and spindle-associated protein
    CLIA Kit for Human Centriole, cilia and spindle-associated protein
    Polyclonal Antibody for Human Centriole, cilia and spindle-associated protein
    Polyclonal Antibody for Human Centriole, cilia and spindle-associated protein
    Monoclonal Antibody for Human Centriole, cilia and spindle-associated protein
    Monoclonal Antibody for Human Centriole, cilia and spindle-associated protein
    Protein for Human Centriole, cilia and spindle-associated protein
    Protein for Human Centriole, cilia and spindle-associated protein

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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Thalamus.
    2. 2.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4)
      tissue: Brain.
      tissue: Duodenum.
      tissue: Placenta.
    5. 5.
      "CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development."
      Backer C.B. , Gutzman J.H. , Pearson C.G. , Cheeseman I.M.
      Mol. Biol. Cell23:2122-2130(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ASSOCIATION WITH MICROTUBULES;SUBCELLULAR LOCATION
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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