CD1D ELISA Kit for Human(Homo sapiens) | EIAab.comCD1D ELISA Kit for Human(Homo sapiens)

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CD1D (Gene name),

Antigen-presenting glycoprotein CD1d (Protein name ), CD1D_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD1D;

Protein name:

Antigen-presenting glycoprotein CD1d;

Alternative:

R3G1;

CD:

CD1d;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer with B2M (beta-2-microglobulin). Interacts with MHC II.

Function:

Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Endosome membrane Lysosome membrane Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Protein Attributes:

Sequence length:

335

Sequence:

50:

100:

150:

200:

250:

300:

335:

SMGLIALAVL | ACLLFLLIVG | FTSRFKRQTS | YQGVL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

188410

Pfam:

PF07654

UniGene:

Hs.1799

String:

P15813

STRING:

9606.ENSP00000357153

KEGG:

hsa:912

SMR:

P15813

Uniprot:

P15813

FOR

ELISA Kit for Human Antigen-presenting glycoprotein CD1d

CLIA Kit for Human Antigen-presenting glycoprotein CD1d

Polyclonal Antibody for Human Antigen-presenting glycoprotein CD1d

Monoclonal Antibody for Human Antigen-presenting glycoprotein CD1d

Protein for Human Antigen-presenting glycoprotein CD1d

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Two classes of CD1 genes."
Calabi F. , Jarvis J.M. , Martin L. , Milstein C.
Eur. J. Immunol.19:285-292(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Isolation and characterization of a cDNA and gene coding for a fourth CD1 molecule."
Balk S.P. , Bleicher P.A. , Terhorst C.
Proc. Natl. Acad. Sci. U.S.A.86:252-256(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
6.

"Polymorphism of human CD1 genes."
Han M. , Hannick L.I. , DiBrino M. , Robinson M.A.
Tissue Antigens54:122-127(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 19-109;VARIANT SER-64
7.

"Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens."
Martin L.H. , Calabi F. , Milstein C.
Proc. Natl. Acad. Sci. U.S.A.83:9154-9158(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 203-295
8.

"A critical tyrosine residue in the cytoplasmic tail is important for CD1d internalization but not for its basolateral sorting in MDCK cells."
Rodionov D.G. , Nordeng T.W. , Pedersen K. , Balk S.P. , Bakke O.
J. Immunol.162:1488-1495(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MUTAGENESIS OF TYR-331 AND VAL-334
9.

"Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules."
Kang S.-J. , Cresswell P.
EMBO J.21:1650-1660(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH B2M AND MHC II
10.

"CD1d ligands: the good, the bad, and the ugly."
Brutkiewicz R.R.
J. Immunol.177:769-775(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
11.

"Distinct endosomal trafficking requirements for presentation of autoantigens and exogenous lipids by human CD1d molecules."
Chen X. , Wang X. , Keaton J.M. , Reddington F. , Illarionov P.A. , Besra G.S. , Gumperz J.E.
J. Immunol.178:6181-6190(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
12.

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-60
tissue: Leukemic T-cell.
13.

"The crystal structure of human CD1d with and without alpha-galactosylceramide."
Koch M. , Stronge V.S. , Shepherd D. , Gadola S.D. , Mathew B. , Ritter G. , Fersht A.R. , Besra G.S. , Schmidt R.R. , Jones E.Y. , Cerundolo V.
Nat. Immunol.6:819-826(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 19-299 IN COMPLEX WITH B2M AND GALACTOSYLCERAMIDE;DISULFIDE BONDS
14.

"CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor."
Borg N.A. , Wun K.S. , Kjer-Nielsen L. , Wilce M.C.J. , Pellicci D.G. , Koh R. , Besra G.S. , Bharadwaj M. , Godfrey D.I. , McCluskey J. , Rossjohn J.
Nature448:44-49(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 24-295 IN COMPLEX WITH B2M AND T-CELL RECEPTOR;GLYCOSYLATION AT ASN-38 AND ASN-60

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