Gene name:
Cd244 (2b4;Nmrk) ;
Protein name:
Natural killer cell receptor 2B4 ;
Alternative:
Non-MHC restricted killing associated ;NK cell type I receptor protein 2B4 (NKR2B4) ;Signaling lymphocytic activation molecule 4 ;SLAM family member 4 (SLAMF4) ;
CD:
CD244 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CD48. Following phosphorylation, it is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. Binding of SH2D1A/SAP to CD244 prevents its association with PTPN11/SHP-2.
Function:
Modulate other receptor-ligand interactions to enhance leukocyte activation.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MLGQAVLFTT | FLLLRAHQGQ | DCPDSSEEVV | GVSGKPVQLR | PSNIQTKDVS |
100:
VQWKKTEQGS | HRKIEILNWY | NDGPSWSNVS | FSDIYGFDYG | DFALSIKSAK |
150:
LQDSGHYLLE | ITNTGGKVCN | KNFQLLILDH | VETPNLKAQW | KPWTNGTCQL |
200:
FLSCLVTKDD | NVSYALYRGS | TLISNQRNST | HWENQIDASS | LHTYTCNVSN |
250:
RASWANHTLN | FTHGCQSVPS | NFRFLPFGVI | IVILVTLFLG | AIICFCVWTK |
300:
KRKQLQFSPK | EPLTIYEYVK | DSRASRDQQG | CSRASGSPSA | VQEDGRGQRE |
350:
LDRRVSEVLE | QLPQQTFPGD | RGTMYSMIQC | KPSDSTSQEK | CTVYSVVQPS |
397:
RKSGSKKRNQ | NSSLSCTVYE | EVGNPWLKAH | NPARLSRREL | ENFDVYS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse Natural killer cell receptor 2B4
ELISA Kit for Mouse Natural killer cell receptor 2B4
ELISA Kit for Mouse Natural killer cell receptor 2B4
CLIA Kit for Mouse Natural killer cell receptor 2B4
CLIA Kit for Mouse Natural killer cell receptor 2B4
CLIA Kit for Mouse Natural killer cell receptor 2B4
Polyclonal Antibody for Mouse Natural killer cell receptor 2B4
Polyclonal Antibody for Mouse Natural killer cell receptor 2B4
Polyclonal Antibody for Mouse Natural killer cell receptor 2B4
Monoclonal Antibody for Mouse Natural killer cell receptor 2B4
Monoclonal Antibody for Mouse Natural killer cell receptor 2B4
Monoclonal Antibody for Mouse Natural killer cell receptor 2B4
Protein for Mouse Natural killer cell receptor 2B4
Protein for Mouse Natural killer cell receptor 2B4
Protein for Mouse Natural killer cell receptor 2B4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
C57BL/6 .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
A.CA .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
strain :
C57BL/6 .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
tissue :
Bone .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 21-129;DISULFIDE BOND
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.63 ANGSTROMS) OF 19-129 ALONE AND IN COMPLEX WITH CD48;DISULFIDE BOND