Protein name:
Cell division cycle-associated 7-like protein ;
Alternative:
Transcription factor RAM2 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with MYC and PSIP1.
Function:
Play a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Play an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells (By similarity). Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Subcellular Location:
Cytoplasm
Nucleus
Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Protein Attributes:
50:
MELATRSQIP | KEVADIFSAP | SDDEEFVGFQ | DDVPMQNLSE | SCGSLDSREL |
100:
EKQQNVCFRS | KYFTEELRRI | FKEDTDSEME | DFEGFTESEL | NMSSNPELME |
150:
SELSDSDKAY | PVMNDAEEDD | EEEAAPRRGR | STRRSSFGLR | VAFQFPTKKL |
200:
ARTPDKDSSH | LLDSKTDLRR | KKSSRQPKGK | EDSASDAEDE | SRAESQENSD |
250:
ALLKRAMNIK | ENKAMLAQLL | AELNSVPDFF | PVRTPPSASR | RRTPRRAFSE |
300:
GQITRRMNPT | RSARPPEKFA | LENFTFSATK | LTEELYSFRR | RKTISGGKCQ |
350:
TYRRHRISSF | RSVKDITEED | LENIAITVRD | KVYDKVLGNT | CHQCRQKTID |
400:
TKTVCRNQSC | GGVRGQFCGP | CLRNRYGEDV | RTALLDPKWT | CPPCRGICNC |
438:
SYCRRRDGRC | ATGILIHLAK | FYGYDNVKEY | LESLQKQL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse Cell division cycle-associated 7-like protein
ELISA Kit for Mouse Cell division cycle-associated 7-like protein
ELISA Kit for Mouse Cell division cycle-associated 7-like protein
CLIA Kit for Mouse Cell division cycle-associated 7-like protein
CLIA Kit for Mouse Cell division cycle-associated 7-like protein
CLIA Kit for Mouse Cell division cycle-associated 7-like protein
Polyclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Polyclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Polyclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Monoclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Monoclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Monoclonal Antibody for Mouse Cell division cycle-associated 7-like protein
Protein for Mouse Cell division cycle-associated 7-like protein
Protein for Mouse Cell division cycle-associated 7-like protein
Protein for Mouse Cell division cycle-associated 7-like protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Bone marrow .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION