Cdc42 ELISA Kit for Mouse(Mus musculus) | EIAab.comCdc42 ELISA Kit for Mouse(Mus musculus)

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Cdc42 (Gene name),

Cell division control protein 42 homolog (Protein name ), CDC42_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cdc42;

Protein name:

Cell division control protein 42 homolog;

Alternative:

G25K GTP-binding protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with CDC42EP1, CDC42EP2, CDC42EP3, CDC42EP4, CDC42EP5, CDC42SE1, CDC42SE2, PARD6A, PARD6B and PARD6G (in a GTP-dependent manner). Interacts with activated CSPG4 and with BAIAP2. Interacts with Zizimin1/DOCK9 and Zizimin2/DOCK11, which activate it by exchanging GDP for GTP. Interacts with NET1 and ARHGAP33/TCGAP. Part of a complex with PARD3, PARD6A or PARD6B and PRKCI or PRKCZ. The GTP-bound form interacts with CCPG1. Interacts with USP6 (By similarity). Interacts with NEK6.

Function:

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia.

Subcellular Location:

Cell membrane Lipid-anchor Cytoplasmic side Cytoplasm cytoskeleton centrosome Co-localizes with NEK6 in the centrosome.

Protein Attributes:

Sequence length:

191

Sequence:

50:

100:

150:

191:

AVKYVECSAL | TQKGLKNVFD | EAILAALEPP | EPKKSRRCVL | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P60766

Pfam:

PF00071

KEGG:

mmu:12540

UniGene:

Mm.1022

String:

P60766

Uniprot:

P60766

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ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321h

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96T

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ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321b

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96T

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ELISA Kit for Mouse Cell division control protein 42 homolog

Cat.:

E0321m

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96T

ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321p

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96T

ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321d

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96T

ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321r

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96T

ELISA Kit for Mouse Cell division control protein 42 homolog

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E0321c

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96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321m

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96T

CLIA Kit for Mouse Cell division control protein 42 homolog

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U0321d

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96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321r

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96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321b

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Packing:

96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321p

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321c

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96T

CLIA Kit for Mouse Cell division control protein 42 homolog

Cat.:

U0321h

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Manual:

Looking for manual.

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96T

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Polyclonal Antibody for Mouse Cell division control protein 42 homolog

Cat.:

P0321Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Cell division control protein 42 homolog

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P0321Rb-r

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Polyclonal Antibody for Mouse Cell division control protein 42 homolog

Cat.:

P0321Rb-m

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Monoclonal Antibody for Mouse Cell division control protein 42 homolog

Protein for Mouse Cell division control protein 42 homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Oncogene ect2 is related to regulators of small GTP-binding proteins."
Miki T. , Smith C.L. , Long J.E. , Eva A. , Fleming T.P.
Nature362:462-465(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
2.

"Complete cDNAs for CDC42 from chicken cochlea and mouse liver."
Gong T.W. , Shin J.J. , Burmeister M. , Lomax M.I.
Biochim. Biophys. Acta1352:282-292(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Liver.
3.

"Genomic organization and chromosomal location of murine Cdc42."
Marks P.W. , Kwiatkowski D.J.
Genomics38:13-18(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
strain: C57BL/6.
tissue: Brain.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: BALB/c.
strain: C57BL/6J.
strain: DBA/2.
strain: NOD.
tissue: Amnion.
tissue: Bone marrow.
tissue: Heart.
tissue: Kidney.
tissue: Liver.
tissue: Mammary gland.
tissue: Placenta.
tissue: Spinal ganglion.
tissue: Thymus.
5.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: C57BL/6J.
tissue: Embryonic germ cell.
7.

Lubec G. , Klug S.
Submitted (2007-03) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 108-120;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Hippocampus.
8.

"The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins."
Joberty G. , Perlungher R.R. , Macara I.G.
Mol. Cell. Biol.19:6585-6597(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDC42EP4
9.

"The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42."
Joberty G. , Petersen C. , Gao L. , Macara I.G.
Nat. Cell Biol.2:531-539(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT OF A COMPLEX CONTAINING PARD6B; PARD3 AND PRKCZ;MUTAGENESIS OF THR-17
10.

"Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7."
Alberts A.S. , Bouquin N. , Johnston L.H. , Treisman R.
J. Biol. Chem.273:8616-8622(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NET1
11.

"TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport."
Chiang S.-H. , Hwang J. , Legendre M. , Zhang M. , Kimura A. , Saltiel A.R.
EMBO J.22:2679-2691(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARHGAP33/TCGAP
12.

"Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes."
Nishikimi A. , Meller N. , Uekawa N. , Isobe K. , Schwartz M.A. , Maruyama M.
FEBS Lett.579:1039-1046(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DOCK11
13.

"Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42."
Lin Q. , Yang W. , Baird D. , Feng Q. , Cerione R.A.
J. Biol. Chem.281:35253-35262(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DOCK11 AND IQGAP1;MUTAGENESIS OF THR-17 AND GLN-61
14.

"Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs."
Kostenko E.V. , Olabisi O.O. , Sahay S. , Rodriguez P.L. , Whitehead I.P.
Mol. Cell. Biol.26:8964-8975(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CCPG1

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