Gene name:
CEP290 (NPHP6) ;
Protein name:
Centrosomal protein of 290 kDa (Cep290) ;
Alternative:
Nephrocystin-6 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with ATF4 via its N-terminal region. Part of selected centrosomal and microtubule-associated protein complexes.
Function:
Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.
Subcellular Location:
Cytoplasm
cytoskeleton
centrosome
Nucleus
Cell projection
cilium
Connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells.
Protein Attributes:
50:
ERQLRKENGK | QKNELMAMEA | EVGEKIGRLQ | RFKEMAVFKI | AALQKVVDNS |
100:
VSLSELELAN | RQYNELTAKY | RDILQKDNML | VQRTNNLEHL | ECENVSLKEQ |
150:
MESINKELEI | TKEKLHTIEQ | AWEQETKLGN | ESNMDKAKKS | VTNSEIVSIS |
200:
KKITMLEMKE | LNERQRAEHS | QKMYEHVKTS | LQQVEERNFE | LETKFAELTR |
250:
INLEAQKVEQ | MLRDELADSV | SKTVSDADRQ | HILELEKSEM | ELKVEVSKLK |
300:
EISDIAKRQV | EILNAQQQSR | EKEVESLRTQ | LLDYQAQSDE | KALIAKLHQH |
350:
VVSLQASEAA | ALGKVESVAS | KLQKVEAHTL | RLEQKLDEKE | QALFYARLEG |
400:
RNRAKHLRQT | IQSLRRQFSG | ALPLAQQEKF | SKTMIQLQND | KLKIMEEMKN |
450:
SQQEHRSLKN | KTLEMELKLK | GLEDLISTLK | DARGAQKVIS | WHTKIEELRL |
500:
QELKLNRELV | KDKEEIKYLN | NIISEYENTI | SSLEEEIVQQ | NKFHEERQMA |
550:
WDQREVELER | QLDVFDRQQS | EILREAQKFE | EATGSMPDPS | LPIPNQLEIA |
600:
LRKIKENIRI | ILETQATCRS | LEEKLREKES | ALRLAEENIL | SRDKVINELR |
650:
LRLPATAEQE | KLLAEFSRKE | VEPKSHHTLK | LAHQTIANMQ | ARLNQKEEVL |
700:
KKYQHLLEKA | REEQREIVKK | HEEELHTLHR | KLELQADNSL | SKFKETAWDL |
750:
IKQSPTPVPT | NKHFIRLAEM | EQTVAEQDDS | LSSLVIKLKQ | VSQDLERQKE |
800:
ITELKIKEFE | NMKLRLQENH | ADEVKKIKAE | VEDLRCLLVQ | SQKESQSLKS |
850:
ELQTQKEANS | RAPTTTMRNL | VERLKSQLAL | KEKQQKALSR | ALLELRAEMT |
900:
AAAEERIISM | TSQKEANLNV | QQIVDRHTKE | LKSQIEDLNE | NILKLKEALK |
950:
TSKNRENTLT | DNLNDLTNEL | QNKQKAYGKV | LREKDAVDQE | NNELKRQIKR |
1000:
LTSGLQGKPL | IDNKQSLIEE | LQKKIKKLES | QLERKVDEAE | MKPMKEKSAR |
1050:
EEVIRWEEGK | KWQTKIEGIR | NKLKEKEGEV | YILTKQLTTL | KDLFAKADKE |
1100:
KLTLQRKLKT | TGLTVDQVMA | ARVLESEKEL | EELKKRNLDL | ENDISYMRSH |
1150:
QALPRDSVIE | DLHLQNKYLQ | EKLHALEKQL | SKDAYSRPST | SGIDSDDHYQ |
1200:
REQELQRENL | KLSSENIELK | FQLEQANKDL | PRLKNQVRDL | KEMCEFLKKE |
1250:
KAEVERKLGR | VRGSGRSGKT | IPELEKTIGL | MKKVVEKVQR | ENEQLKKASG |
1300:
ILTSEKMANI | EMENEKLKAE | LEKLKVHLGR | QLSMHYESKA | KGTEKIVAEN |
1350:
ERLRKELKKI | EILKHVPEGD | ETEQGLQREL | RVLRLANSQL | EKEKEELIHR |
1400:
IEISKDQNGP | DSTISDPDHL | MEKIKDLETQ | LRTSDMEKQH | LKEEIQKLKK |
1450:
ELENFDPSFF | EEIEDLKYNY | KEEVKKNILL | EEKLKKLSEQ | FGVELTSPVA |
1468:
ASEQFEDEQE | NPVNFPIY
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Bovine Cep290
ELISA Kit for Bovine Cep290
ELISA Kit for Bovine Cep290
CLIA Kit for Bovine Cep290
CLIA Kit for Bovine Cep290
CLIA Kit for Bovine Cep290
Polyclonal Antibody for Bovine Cep290
Polyclonal Antibody for Bovine Cep290
Polyclonal Antibody for Bovine Cep290
Monoclonal Antibody for Bovine Cep290
Monoclonal Antibody for Bovine Cep290
Monoclonal Antibody for Bovine Cep290
Protein for Bovine Cep290
Protein for Bovine Cep290
Protein for Bovine Cep290
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Trachea .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 685-1468 (ISOFORM 2)
strain :
Hereford .
tissue :
Basal ganglia .
3.
"FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies."
Di Gioia S.A.
,
Letteboer S.J.
,
Kostic C.
,
Bandah-Rozenfeld D.
,
Hetterschijt L.
,
Sharon D.
,
Arsenijevic Y.
,
Roepman R.
,
Rivolta C.
Hum. Mol. Genet.21:5174-5184(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH FAM161A