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Index > Protein center > CEP290(Gene name) > Bovine
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  • CEP290 (Gene name),
  • Centrosomal protein of 290 kDa (Protein name ),  CE290_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CEP290(NPHP6);
    Protein name:
    Centrosomal protein of 290 kDa(Cep290);
    Alternative:
    Nephrocystin-6;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with ATF4 via its N-terminal region. Part of selected centrosomal and microtubule-associated protein complexes.
    Function:
    Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.
    Subcellular Location:
    Cytoplasm cytoskeleton centrosome Nucleus Cell projection cilium Connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells.
    Protein Attributes:
    Sequence length:
    1468
    Sequence:
    50:
    ERQLRKENGK | QKNELMAMEA | EVGEKIGRLQ | RFKEMAVFKI | AALQKVVDNS | 
    100:
    VSLSELELAN | RQYNELTAKY | RDILQKDNML | VQRTNNLEHL | ECENVSLKEQ | 
    150:
    MESINKELEI | TKEKLHTIEQ | AWEQETKLGN | ESNMDKAKKS | VTNSEIVSIS | 
    200:
    KKITMLEMKE | LNERQRAEHS | QKMYEHVKTS | LQQVEERNFE | LETKFAELTR | 
    250:
    INLEAQKVEQ | MLRDELADSV | SKTVSDADRQ | HILELEKSEM | ELKVEVSKLK | 
    300:
    EISDIAKRQV | EILNAQQQSR | EKEVESLRTQ | LLDYQAQSDE | KALIAKLHQH | 
    350:
    VVSLQASEAA | ALGKVESVAS | KLQKVEAHTL | RLEQKLDEKE | QALFYARLEG | 
    400:
    RNRAKHLRQT | IQSLRRQFSG | ALPLAQQEKF | SKTMIQLQND | KLKIMEEMKN | 
    450:
    SQQEHRSLKN | KTLEMELKLK | GLEDLISTLK | DARGAQKVIS | WHTKIEELRL | 
    500:
    QELKLNRELV | KDKEEIKYLN | NIISEYENTI | SSLEEEIVQQ | NKFHEERQMA | 
    550:
    WDQREVELER | QLDVFDRQQS | EILREAQKFE | EATGSMPDPS | LPIPNQLEIA | 
    600:
    LRKIKENIRI | ILETQATCRS | LEEKLREKES | ALRLAEENIL | SRDKVINELR | 
    650:
    LRLPATAEQE | KLLAEFSRKE | VEPKSHHTLK | LAHQTIANMQ | ARLNQKEEVL | 
    700:
    KKYQHLLEKA | REEQREIVKK | HEEELHTLHR | KLELQADNSL | SKFKETAWDL | 
    750:
    IKQSPTPVPT | NKHFIRLAEM | EQTVAEQDDS | LSSLVIKLKQ | VSQDLERQKE | 
    800:
    ITELKIKEFE | NMKLRLQENH | ADEVKKIKAE | VEDLRCLLVQ | SQKESQSLKS | 
    850:
    ELQTQKEANS | RAPTTTMRNL | VERLKSQLAL | KEKQQKALSR | ALLELRAEMT | 
    900:
    AAAEERIISM | TSQKEANLNV | QQIVDRHTKE | LKSQIEDLNE | NILKLKEALK | 
    950:
    TSKNRENTLT | DNLNDLTNEL | QNKQKAYGKV | LREKDAVDQE | NNELKRQIKR | 
    1000:
    LTSGLQGKPL | IDNKQSLIEE | LQKKIKKLES | QLERKVDEAE | MKPMKEKSAR | 
    1050:
    EEVIRWEEGK | KWQTKIEGIR | NKLKEKEGEV | YILTKQLTTL | KDLFAKADKE | 
    1100:
    KLTLQRKLKT | TGLTVDQVMA | ARVLESEKEL | EELKKRNLDL | ENDISYMRSH | 
    1150:
    QALPRDSVIE | DLHLQNKYLQ | EKLHALEKQL | SKDAYSRPST | SGIDSDDHYQ | 
    1200:
    REQELQRENL | KLSSENIELK | FQLEQANKDL | PRLKNQVRDL | KEMCEFLKKE | 
    1250:
    KAEVERKLGR | VRGSGRSGKT | IPELEKTIGL | MKKVVEKVQR | ENEQLKKASG | 
    1300:
    ILTSEKMANI | EMENEKLKAE | LEKLKVHLGR | QLSMHYESKA | KGTEKIVAEN | 
    1350:
    ERLRKELKKI | EILKHVPEGD | ETEQGLQREL | RVLRLANSQL | EKEKEELIHR | 
    1400:
    IEISKDQNGP | DSTISDPDHL | MEKIKDLETQ | LRTSDMEKQH | LKEEIQKLKK | 
    1450:
    ELENFDPSFF | EEIEDLKYNY | KEEVKKNILL | EEKLKKLSEQ | FGVELTSPVA | 
    1468:
    ASEQFEDEQE | NPVNFPIY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Uniprot:
     
    FOR
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    Packing:
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    Polyclonal Antibody for Bovine Cep290
    Monoclonal Antibody for Bovine Cep290
    Monoclonal Antibody for Bovine Cep290
    Monoclonal Antibody for Bovine Cep290
    Protein for Bovine Cep290
    Protein for Bovine Cep290
    Protein for Bovine Cep290

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    References
    1. 1.
      Jovov B. , Ripoll P.J. , Benos D.J.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Trachea.
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 685-1468 (ISOFORM 2)
      strain: Hereford.
      tissue: Basal ganglia.
    3. 3.
      "FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies."
      Di Gioia S.A. , Letteboer S.J. , Kostic C. , Bandah-Rozenfeld D. , Hetterschijt L. , Sharon D. , Arsenijevic Y. , Roepman R. , Rivolta C.
      Hum. Mol. Genet.21:5174-5184(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM161A
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