CUGBP Elav-like family member 3 (Protein name
), CELF3_MOUSE from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
Celf3(Tnrc4);
Protein name:
CUGBP Elav-like family member 3(CELF-3);
Alternative:
CUG-BP- and ETR-3-like factor 3;Bruno-like protein 1;RNA-binding protein BRUNOL-1;ELAV-type RNA-binding protein 1(ETR-1);Trinucleotide repeat-containing gene 4 protein;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
N/A
Function:
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
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Precision
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Recovery
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Linearity
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References
1.
"The RNA binding protein CELF3 associates to the DMPK mRNA and is a negative regulator of mRNA stability involved in neuronal differentiation." d'Apolito M.
,
Savino M.
,
Grifa A.
,
Quattrone A.
Submitted (2002-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)