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Index > Protein center > Celf4(Gene name) > Mouse
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  • Celf4 (Gene name),
  • CUGBP Elav-like family member 4 (Protein name ),  CELF4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Celf4(Brul4;Brunol4);
    Protein name:
    CUGBP Elav-like family member 4(CELF-4);
    Alternative:
    CUG-BP- and ETR-3-like factor 4;Bruno-like protein 4;RNA-binding protein BRUNOL-4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
    Subcellular Location:
    Nucleus Cytoplasm
    Protein Attributes:
    Sequence length:
    486
    Sequence:
    50:
    MYIKMATLAN | GQADNASLST | NGLGSSPGSA | GHMNGLSHSP | GNPSTIPMKD | 
    100:
    HDAIKLFIGQ | IPRNLDEKDL | KPLFEEFGKI | YELTVLKDRF | TGMHKGCAFL | 
    150:
    TYCERESALK | AQSALHEQKT | LPGMNRPIQV | KPADSESRGG | SSCLRQPPSQ | 
    200:
    DRKLFVGMLN | KQQSEDDVRR | LFEAFGNIEE | CTILRGPDGN | SKGCAFVKYS | 
    250:
    SHAEAQAAIN | ALHGSQTMPG | ASSSLVVKFA | DTDKERTMRR | MQQMAGQMGM | 
    300:
    FNPMAIPFGA | YGAYAQALMQ | QQAALMASVA | QGGYLNPMAA | FAAAQMQQMA | 
    350:
    ALNMNGLAAA | PMTPTSGGST | PPGITAPAVP | SIPSPIGVNG | FTGLPPQANG | 
    400:
    QPAAEAVFAN | GIHPYPAQSP | TAADPLQQAY | AGVQQYAGPA | AYPAAYGQIS | 
    450:
    QAFPQPPPMI | PQQQREGPEG | CNLLIYHLPQ | EFGDAELMQM | FLPFGFVSFD | 
    486:
    NPASAQTAIQ | AMNGFQIGMK | RLKVQLKRPK | DANRPY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CELF-4
    ELISA Kit for Mouse CELF-4
    CLIA Kit for Mouse CELF-4
    CLIA Kit for Mouse CELF-4
    Polyclonal Antibody for Mouse CELF-4
    Polyclonal Antibody for Mouse CELF-4
    Monoclonal Antibody for Mouse CELF-4
    Monoclonal Antibody for Mouse CELF-4
    Protein for Mouse CELF-4
    Protein for Mouse CELF-4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification and characterization of murine Brunol4, a new member of the elav/bruno family."
      Meins M. , Schlickum S. , Wilhelm C. , Missbach J. , Yadav S. , Glaeser B. , Grzmil M. , Burfeind P. , Laccone F.
      Cytogenet. Genome Res.97:254-260(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
      strain: C57BL/6J.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 4 AND 7)
      strain: C57BL/6J.
      tissue: Brain cortex.
      tissue: Head.
      tissue: Spinal ganglion.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 7)
      strain: C57BL/6.
      tissue: Brain.
      tissue: Eye.
    5. 5.
      "A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator."
      Good P.J. , Chen Q. , Warner S.J. , Herring D.C.
      J. Biol. Chem.275:28583-28592(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 188-486 (ISOFORMS 2/3/4/5)
      strain: C57BL/6J.
    6. 6.
      "The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing."
      Ladd A.N. , Charlet-B N. , Cooper T.A.
      Mol. Cell. Biol.21:1285-1296(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
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