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Index > Protein center > CELSR1(Gene name) > Human
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  • CELSR1 (Gene name),
  • Cadherin EGF LAG seven-pass G-type receptor 1 (Protein name ),  CELR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CELSR1(CDHF9;FMI2);
    Protein name:
    Cadherin EGF LAG seven-pass G-type receptor 1;
    Alternative:
    Flamingo homolog 2(hFmi2);Cadherin family member 9;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor that may have an important role in cell/cell signaling during nervous system formation.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    3014
    Sequence:
    50:
    MAPPPPPVLP | VLLLLAAAAA | LPAMGLRAAA | WEPRVPGGTR | AFALRPGCTY | 
    100:
    AVGAACTPRA | PRELLDVGRD | GRLAGRRRVS | GAGRPLPLQV | RLVARSAPTA | 
    150:
    LSRRLRARTH | LPGCGARARL | CGTGARLCGA | LCFPVPGGCA | AAQHSALAAP | 
    200:
    TTLPACRCPP | RPRPRCPGRP | ICLPPGGSVR | LRLLCALRRA | AGAVRVGLAL | 
    250:
    EAATAGTPSA | SPSPSPPLPP | NLPEARAGPA | RRARRGTSGR | GSLKFPMPNY | 
    300:
    QVALFENEPA | GTLILQLHAH | YTIEGEEERV | SYYMEGLFDE | RSRGYFRIDS | 
    350:
    ATGAVSTDSV | LDRETKETHV | LRVKAVDYST | PPRSATTYIT | VLVKDTNDHS | 
    400:
    PVFEQSEYRE | RVRENLEVGY | EVLTIRASDR | DSPINANLRY | RVLGGAWDVF | 
    450:
    QLNESSGVVS | TRAVLDREEA | AEYQLLVEAN | DQGRNPGPLS | ATATVYIEVE | 
    500:
    DENDNYPQFS | EQNYVVQVPE | DVGLNTAVLR | VQATDRDQGQ | NAAIHYSILS | 
    550:
    GNVAGQFYLH | SLSGILDVIN | PLDFEDVQKY | SLSIKAQDGG | RPPLINSSGV | 
    600:
    VSVQVLDVND | NEPIFVSSPF | QATVLENVPL | GYPVVHIQAV | DADSGENARL | 
    650:
    HYRLVDTAST | FLGGGSAGPK | NPAPTPDFPF | QIHNSSGWIT | VCAELDREEV | 
    700:
    EHYSFGVEAV | DHGSPPMSSS | TSVSITVLDV | NDNDPVFTQP | TYELRLNEDA | 
    750:
    AVGSSVLTLQ | ARDRDANSVI | TYQLTGGNTR | NRFALSSQRG | GGLITLALPL | 
    800:
    DYKQEQQYVL | AVTASDGTRS | HTAHVLINVT | DANTHRPVFQ | SSHYTVSVSE | 
    850:
    DRPVGTSIAT | LSANDEDTGE | NARITYVIQD | PVPQFRIDPD | SGTMYTMMEL | 
    900:
    DYENQVAYTL | TIMAQDNGIP | QKSDTTTLEI | LILDANDNAP | QFLWDFYQGS | 
    950:
    IFEDAPPSTS | ILQVSATDRD | SGPNGRLLYT | FQGGDDGDGD | FYIEPTSGVI | 
    1000:
    RTQRRLDREN | VAVYNLWALA | VDRGSPTPLS | ASVEIQVTIL | DINDNAPMFE | 
    1050:
    KDELELFVEE | NNPVGSVVAK | IRANDPDEGP | NAQIMYQIVE | GDMRHFFQLD | 
    1100:
    LLNGDLRAMV | ELDFEVRREY | VLVVQATSAP | LVSRATVHIL | LVDQNDNPPV | 
    1150:
    LPDFQILFNN | YVTNKSNSFP | TGVIGCIPAH | DPDVSDSLNY | TFVQGNELRL | 
    1200:
    LLLDPATGEL | QLSRDLDNNR | PLEALMEVSV | SDGIHSVTAF | CTLRVTIITD | 
    1250:
    DMLTNSITVR | LENMSQEKFL | SPLLALFVEG | VAAVLSTTKD | DVFVFNVQND | 
    1300:
    TDVSSNILNV | TFSALLPGGV | RGQFFPSEDL | QEQIYLNRTL | LTTISTQRVL | 
    1350:
    PFDDNICLRE | PCENYMKCVS | VLRFDSSAPF | LSSTTVLFRP | IHPINGLRCR | 
    1400:
    CPPGFTGDYC | ETEIDLCYSD | PCGANGRCRS | REGGYTCECF | EDFTGEHCEV | 
    1450:
    DARSGRCANG | VCKNGGTCVN | LLIGGFHCVC | PPGEYERPYC | EVTTRSFPPQ | 
    1500:
    SFVTFRGLRQ | RFHFTISLTF | ATQERNGLLL | YNGRFNEKHD | FIALEIVDEQ | 
    1550:
    VQLTFSAGET | TTTVAPKVPS | GVSDGRWHSV | QVQYYNKPNI | GHLGLPHGPS | 
    1600:
    GEKMAVVTVD | DCDTTMAVRF | GKDIGNYSCA | AQGTQTGSKK | SLDLTGPLLL | 
    1650:
    GGVPNLPEDF | PVHNRQFVGC | MRNLSVDGKN | VDMAGFIANN | GTREGCAARR | 
    1700:
    NFCDGRRCQN | GGTCVNRWNM | YLCECPLRFG | GKNCEQAMPH | PQLFSGESVV | 
    1750:
    SWSDLNIIIS | VPWYLGLMFR | TRKEDSVLME | ATSGGPTSFR | LQILNNYLQF | 
    1800:
    EVSHGPSDVE | SVMLSGLRVT | DGEWHHLLIE | LKNVKEDSEM | KHLVTMTLDY | 
    1850:
    GMDQNKADIG | GMLPGLTVRS | VVVGGASEDK | VSVRRGFRGC | MQGVRMGGTP | 
    1900:
    TNVATLNMNN | ALKVRVKDGC | DVDDPCTSSP | CPPNSRCHDA | WEDYSCVCDK | 
    1950:
    GYLGINCVDA | CHLNPCENMG | ACVRSPGSPQ | GYVCECGPSH | YGPYCENKLD | 
    2000:
    LPCPRGWWGN | PVCGPCHCAV | SKGFDPDCNK | TNGQCQCKEN | YYKLLAQDTC | 
    2050:
    LPCDCFPHGS | HSRTCDMATG | QCACKPGVIG | RQCNRCDNPF | AEVTTLGCEV | 
    2100:
    IYNGCPKAFE | AGIWWPQTKF | GQPAAVPCPK | GSVGNAVRHC | SGEKGWLPPE | 
    2150:
    LFNCTTISFV | DLRAMNEKLS | RNETQVDGAR | ALQLVRALRS | ATQHTGTLFG | 
    2200:
    NDVRTAYQLL | GHVLQHESWQ | QGFDLAATQD | ADFHEDVIHS | GSALLAPATR | 
    2250:
    AAWEQIQRSE | GGTAQLLRRL | EGYFSNVARN | VRRTYLRPFV | IVTANMILAV | 
    2300:
    DIFDKFNFTG | ARVPRFDTIH | EEFPRELESS | VSFPADFFRP | PEEKEGPLLR | 
    2350:
    PAGRRTTPQT | TRPGPGTERE | APISRRRRHP | DDAGQFAVAL | VIIYRTLGQL | 
    2400:
    LPERYDPDRR | SLRLPHRPII | NTPMVSTLVY | SEGAPLPRPL | ERPVLVEFAL | 
    2450:
    LEVEERTKPV | CVFWNHSLAV | GGTGGWSARG | CELLSRNRTH | VACQCSHTAS | 
    2500:
    FAVLMDISRR | ENGEVLPLKI | VTYAAVSLSL | AALLVAFVLL | SLVRMLRSNL | 
    2550:
    HSIHKHLAVA | LFLSQLVFVI | GINQTENPFL | CTVVAILLHY | IYMSTFAWTL | 
    2600:
    VESLHVYRML | TEVRNIDTGP | MRFYYVVGWG | IPAIVTGLAV | GLDPQGYGNP | 
    2650:
    DFCWLSLQDT | LIWSFAGPIG | AVIIINTVTS | VLSAKVSCQR | KHHYYGKKGI | 
    2700:
    VSLLRTAFLL | LLLISATWLL | GLLAVNRDAL | SFHYLFAIFS | GLQGPFVLLF | 
    2750:
    HCVLNQEVRK | HLKGVLGGRK | LHLEDSATTR | ATLLTRSLNC | NTTFGDGPDM | 
    2800:
    LRTDLGESTA | SLDSIVRDEG | IQKLGVSSGL | VRGSHGEPDA | SLMPRSCKDP | 
    2850:
    PGHDSDSDSE | LSLDEQSSSY | ASSHSSDSED | DGVGAEEKWD | PARGAVHSTP | 
    2900:
    KGDAVANHVP | AGWPDQSLAE | SDSEDPSGKP | RLKVETKVSV | ELHREEQGSH | 
    2950:
    RGEYPPDQES | GGAARLASSQ | PPEQRKGILK | NKVTYPPPLT | LTEQTLKGRL | 
    3000:
    REKLADCEQS | PTSSRTSSLG | SGGPDCAITV | KSPGREPGRD | HLNGVAMNVR | 
    3014:
    TGSAQADGSD | SEKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    String:
    UniGene:
    MIM:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cadherin EGF LAG seven-pass G-type receptor 1
    ELISA Kit for Human Cadherin EGF LAG seven-pass G-type receptor 1
    CLIA Kit for Human Cadherin EGF LAG seven-pass G-type receptor 1
    CLIA Kit for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Polyclonal Antibody for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Polyclonal Antibody for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Monoclonal Antibody for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Monoclonal Antibody for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Protein for Human Cadherin EGF LAG seven-pass G-type receptor 1
    Protein for Human Cadherin EGF LAG seven-pass G-type receptor 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
      Wu Q. , Maniatis T.
      Proc. Natl. Acad. Sci. U.S.A.97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 627-3014 (ISOFORM 2);VARIANTS TRP-664 AND ARG-1126
      tissue: Kidney.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2764;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    5. 5.
      "Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis."
      Robinson A. , Escuin S. , Doudney K. , Vekemans M. , Stevenson R.E. , Greene N.D. , Copp A.J. , Stanier P.
      Hum. Mutat.33:440-447(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NTD VAL-773; GLN-2438; LEU-2964 AND ALA-2983;VARIANTS PRO-2312 AND THR-2739;CHARACTERIZATION OF VARIANTS NTD VAL-773; GLN-2438; LEU-2964 AND ALA-2983;CHARACTERIZATION OF VARIANTS PRO-2312 AND THR-2739
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