Cenpe ELISA Kit for Mouse(Mus musculus) | EIAab.comCenpe ELISA Kit for Mouse(Mus musculus)

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Cenpe (Gene name),

Centromere-associated protein E (Protein name ), CENPE_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cenpe;

Protein name:

Centromere-associated protein E;

Alternative:

Kinesin superfamily protein 10(KIF10);Centromere protein E(CENP-E);Motor domain of KIF10;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Monomer. Interacts with CENPF, SEPT7 KIF18A and PRC1 (By similarity). Interacts with BUBR1 kinase.

Function:

Essential for the maintenance of chromosomal stability through efficient stabilization of microtubule capture at kinetochores. Plays a key role in the movement of chromosomes toward the metaphase plate during mitosis. Is a slow plus end-directed motor whose activity is essential for metaphase chromosome alignment. Couples chromosome position to microtubule depolymerizing activity. The highly processive microtubule-dependent motor activity of CENPE serves to power chromosome congression and provides a flexible, motile tether linking kinetochores to dynamic spindle microtubules. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss. Required for the efficient recruitment of BUBR1, MAD1 and MAD2 to attached and newly unattached kinetochores. Stimulates mammalian BUBR1 kinase activity. Accumulates just before mitosis at the G2 phase of the cell cycle.

Subcellular Location:

Cytoplasm cytoskeleton spindle Chromosome centromere kinetochore Associates with kinetochores during congression (as early as prometaphase), relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

Protein Attributes:

Sequence length:

2474

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ENVEPKTDLC | QASLEKDVSQ | CKTQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.161470

String:

Q6RT24

Pfam:

PF00225

KEGG:

mmu:229841

SMR:

Q6RT24

STRING:

10090.ENSMUSP00000057938

Uniprot:

Q6RT24

FOR

ELISA Kit for Mouse Centromere-associated protein E

CLIA Kit for Mouse Centromere-associated protein E

Polyclonal Antibody for Mouse Centromere-associated protein E

Monoclonal Antibody for Mouse Centromere-associated protein E

Protein for Mouse Centromere-associated protein E

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

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