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Index > Protein center > Cers4(Gene name) > Mouse
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  • Cers4 (Gene name),
  • Ceramide synthase 4 (Protein name ),  CERS4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cers4(Lass4;Trh1);
    Protein name:
    Ceramide synthase 4(CerS4);
    Alternative:
    Translocating chain-associating membrane protein homolog 1(TRAM homolog 1);LAG1 longevity assurance homolog 4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.
    Subcellular Location:
    Nucleus membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    393
    Sequence:
    50:
    MSFSLSEWLW | QETYWLPPNV | TWAELEDRDG | LVFAHPHHVL | AAFPVALVLV | 
    100:
    AVRIVFERFV | ALPLSRWMGV | QDPIRRKIKP | NPVLEKYFLR | MKQCPEETQM | 
    150:
    VLLASQCGLT | LRQTQRWFRR | RRNQDRPSLS | KKFCEACWRF | VFYLCSFVGG | 
    200:
    TSILYHESWL | WSPSLCWENY | PHQTLNLSLY | WWYLLELGFY | LSLLITLPFD | 
    250:
    VKRKDFKEQV | VHHFVAVGLI | GFSYSVNLLR | IGAVVLLLHD | CSDYLLEGCK | 
    300:
    ILNYAHFRRG | CDALFIMFAL | VFFYTRLIFF | PTQVIYTSVY | DSIKNSGPFF | 
    350:
    GYYFFIVLLV | MLQILHVYWF | CLILRMLYSF | LHKGQMTEDI | RSDVEEPDSS | 
    393:
    DDEPVSEGPQ | LKNGMARGSR | VAVTNGPRSR | AAACLTNGHT | RAT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CerS4
    ELISA Kit for Mouse CerS4
    ELISA Kit for Mouse CerS4
    CLIA Kit for Mouse CerS4
    CLIA Kit for Mouse CerS4
    CLIA Kit for Mouse CerS4
    Polyclonal Antibody for Mouse CerS4
    Polyclonal Antibody for Mouse CerS4
    Polyclonal Antibody for Mouse CerS4
    Monoclonal Antibody for Mouse CerS4
    Monoclonal Antibody for Mouse CerS4
    Monoclonal Antibody for Mouse CerS4
    Protein for Mouse CerS4
    Protein for Mouse CerS4
    Protein for Mouse CerS4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Hartmann E.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Hippocampus.
      tissue: Skin.
      tissue: Stomach.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
    4. 4.
      "Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors."
      Riebeling C. , Allegood J.C. , Wang E. , Merrill A.H. Jr. , Futerman A.H.
      J. Biol. Chem.278:43452-43459(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CERAMIDE SYNTHESIS;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    5. 5.
      "Mammalian Lass6 and its related family members regulate synthesis of specific ceramides."
      Mizutani Y. , Kihara A. , Igarashi Y.
      Biochem. J.390:263-271(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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