MB21D1 ELISA Kit for Bovine(Bos taurus) | EIAab.comMB21D1 ELISA Kit for Bovine(Bos taurus) | EIAab.com

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MB21D1 (Gene name),

Cyclic GMP-AMP synthase (Protein name ), CGAS_BOVIN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

MB21D1;

Protein name:

Cyclic GMP-AMP synthase(cGAMP synthase);

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

N/A

Function:

Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. Has antiviral activity by acting as a key cytosolic DNA sensor, the presence of double-stranded DNA (dsDNA) in the cytoplasm being a danger signal that triggers the immune responses. Binds cytosolic DNA directly, leading to activation and synthesis of cGAMP, a second messenger that binds to and activates TMEM173/STING, thereby triggering type-I interferon production.

Subcellular Location:

Cytoplasm Cytosol

Protein Attributes:

Sequence length:

498

Sequence:

50:

MAPPRRKATR | KASETASGVS | APCVEGGLSA | EPSEPAAVPE | APRPGARRCG |

100:

AAGASGSRRE | KSRLDPREKP | QVRARAARAE | DQAEGPAAPT | ADAEPPAAPG |

150:

HSLPRASTRS | RGTASSARAR | RPQSGPPEGP | GLGPRAPSPH | LGRREEAPGA |

200:

WKPRAVLEKL | KLSRQEISVA | AEVVNRLGDH | LLRRLNSRES | EFKGVDLLRT |

250:

GSYYERVKIS | APNEFDLMFT | LEVPRIQLEE | YCNSSAHYFV | KFKRNPKGSP |

300:

LDQFLEGGIL | SASKMLFKFR | KIIKEEIKHI | EDTDVIMERK | KRGSPAVTLL |

350:

IRKPREISVD | IILALESKSS | WPASTQKGLP | ISNWLGTKVK | DNLKRQPFYL |

400:

VPKHAKEGSL | FQEETWRLSF | SHIEKAILTN | HGQTKTCCET | EGVKCCRKEC |

450:

LKLMKYLLEQ | LKKKFGKQRG | LDKFCSYHVK | TAFLHVCTQN | PHDSWWLYKD |

498:

LELCFDNCVT | YFLQCLKTEH | LEHYFIPDVL | SKQIEYEQNN | GFPVFDEF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

Uniprot:

FOR

ELISA Kit for Bovine cGAMP synthase

ELISA Kit for Bovine cGAMP synthase

ELISA Kit for Bovine cGAMP synthase

ELISA Kit for Bovine cGAMP synthase

ELISA Kit for Bovine cGAMP synthase

CLIA Kit for Bovine cGAMP synthase

CLIA Kit for Bovine cGAMP synthase

CLIA Kit for Bovine cGAMP synthase

CLIA Kit for Bovine cGAMP synthase

CLIA Kit for Bovine cGAMP synthase

Polyclonal Antibody for Bovine cGAMP synthase

Polyclonal Antibody for Bovine cGAMP synthase

Polyclonal Antibody for Bovine cGAMP synthase

Polyclonal Antibody for Bovine cGAMP synthase

Polyclonal Antibody for Bovine cGAMP synthase

Monoclonal Antibody for Bovine cGAMP synthase

Monoclonal Antibody for Bovine cGAMP synthase

Monoclonal Antibody for Bovine cGAMP synthase

Monoclonal Antibody for Bovine cGAMP synthase

Monoclonal Antibody for Bovine cGAMP synthase

Protein for Bovine cGAMP synthase

Protein for Bovine cGAMP synthase

Protein for Bovine cGAMP synthase

Protein for Bovine cGAMP synthase

Protein for Bovine cGAMP synthase

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V. , Delcher A.L. , Florea L. , Kelley D.R. , Schatz M.C. , Puiu D. , Hanrahan F. , Pertea G. , Van Tassell C.P. , Sonstegard T.S. , Marcais G. , Roberts M. , Subramanian P. , Yorke J.A. , Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Hereford.

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