Gene name:
CSGALNACT1 (UNQ656/PRO1287;CHGN;GALNACT1) ;
Protein name:
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) ;
Alternative:
Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1 (Beta4GalNAcT-1) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.
Subcellular Location:
Golgi apparatus
Golgi stack membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MMMVRRGLLA | WISRVVVLLV | LLCCAISVLY | MLACTPKGDE | EQLALPRANS |
100:
PTGKEGYQAV | LQEWEEQHRN | YVSSLKRQIA | QLKEELQERS | EQLRNGQYQA |
150:
SDAAGLGLDR | SPPEKTQADL | LAFLHSQVDK | AEVNAGVKLA | TEYAAVPFDS |
200:
FTLQKVYQLE | TGLTRHPEEK | PVRKDKRDEL | VEAIESALET | LNSPAENSPN |
250:
HRPYTASDFI | EGIYRTERDK | GTLYELTFKG | DHKHEFKRLI | LFRPFGPIMK |
300:
VKNEKLNMAN | TLINVIVPLA | KRVDKFRQFM | QNFREMCIEQ | DGRVHLTVVY |
350:
FGKEEINEVK | GILENTSKAA | NFRNFTFIQL | NGEFSRGKGL | DVGARFWKGS |
400:
NVLLFFCDVD | IYFTSEFLNT | CRLNTQPGKK | VFYPVLFSQY | NPGIIYGHHD |
450:
AVPPLEQQLV | IKKETGFWRD | FGFGMTCQYR | SDFINIGGFD | LDIKGWGGED |
500:
VHLYRKYLHS | NLIVVRTPVR | GLFHLWHEKR | CMDELTPEQY | KMCMQSKAMN |
532:
EASHGQLGML | VFRHEIEAHL | RKQKQKTSSK | KT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human CsGalNAcT-1
ELISA Kit for Human CsGalNAcT-1
CLIA Kit for Human CsGalNAcT-1
CLIA Kit for Human CsGalNAcT-1
Polyclonal Antibody for Human CsGalNAcT-1
Polyclonal Antibody for Human CsGalNAcT-1
Monoclonal Antibody for Human CsGalNAcT-1
Monoclonal Antibody for Human CsGalNAcT-1
Protein for Human CsGalNAcT-1
Protein for Human CsGalNAcT-1
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;GLYCOSYLATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;VARIANT ASN-193
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Melanoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;VARIANT ASN-193
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT ASN-193
tissue :
Placenta .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 381-532;VARIANT ASN-193
tissue :
Melanoma .
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"Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate."
Sato T.
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Gotoh M.
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Akashima T.
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J. Biol. Chem.278:3063-3071(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION